Name	Description	pvalue	qvalue	phenotype	genes
EXTRACELLULAR MATRIX ORGANIZATION%REACTOME%R-HSA-1474244.5	Extracellular matrix organization	3.83666097632802e-20	3.83666097632802e-20	1	COL6A1,SERPINE1,SNTB1,P3H2,TIMP2,P3H3,COL6A2,COL5A1,ITGA5,FBLN1,FBN1,LOX,BGN,ADAM12,LAMB3,LOXL2,COL12A1,COL27A1,CD44,ITGB4,FGF2,HTRA1,PCOLCE2,TNC,PLOD1,TIMP1,PXDN,LAMB1,ITGA3,COL13A1,ADAMTS16,COL18A1,ITGAX,MMP24,LRP4,COL6A3,P3H1,CRTAP,ADAMTS14,LAMA4,LAMC3,SDC2,ITGB3,LAMC2,LAMA5,MMP19,TNXB,PLEC,BMP7,SNTA1,TGFB1,P4HA2,COLGALT1,ADAM19,AGRN,LTBP3,HSPG2,FBLN2,LOXL1,MFAP4,BMP1,MFAP2,LOXL4,PLOD3,CD151,COL9A3,ITGA6,COL23A1,ACTN1,PPIB,ITGB2,MMP15,FURIN
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION%MSIGDBHALLMARK%HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION%MSIGDBHALLMARK%HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION%MSIGDBHALLMARK%HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION%MSigdbHallmark%HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	5.35241867379611e-16	5.35241867379611e-16	1	SNTB1,TGFBI,FBN1,SERPINE2,ADAM12,CTGF,LOXL2,COL12A1,CD44,NT5E,FGF2,SPOCK1,HTRA1,PCOLCE2,TNC,PLOD1,TIMP1,MYLK,FZD8,FSTL3,TFPI2,PLAUR,NNMT,WIPF1,GAS1,P3H1,ITGB3,GPC1,LAMC2,EMP3,TGFB1,CDH2,COLGALT1,FBLN2,LOXL1,BMP1,SLIT3,SLIT2,PLOD3,ENO2,CYR61,PPIB,BASP1,CADM1,APLP1,SNAI2,GADD45A
COLLAGEN FORMATION%REACTOME DATABASE ID RELEASE 97%1474290	Collagen formation	2.11567011166605e-14	2.11567011166605e-14	1	COL6A1,P3H2,P3H3,COL6A2,COL5A1,LOX,LAMB3,LOXL2,COL12A1,COL27A1,ITGB4,PCOLCE2,PLOD1,PXDN,COL13A1,COL18A1,COL6A3,P3H1,CRTAP,ADAMTS14,LAMC2,PLEC,P4HA2,COLGALT1,LOXL1,BMP1,LOXL4,PLOD3,CD151,COL9A3,ITGA6,COL23A1,PPIB
HALLMARK_HYPOXIA%MSIGDBHALLMARK%HALLMARK_HYPOXIA%MSIGDBHALLMARK%HALLMARK_HYPOXIA%MSIGDBHALLMARK%HALLMARK_HYPOXIA	HALLMARK_HYPOXIA%MSigdbHallmark%HALLMARK_HYPOXIA	1.51461073536989e-11	1.51461073536989e-11	1	F3,TGFBI,ANGPTL4,SRPX,CTGF,EGFR,ADM,CAVIN1,DPYSL4,KLF7,CHST3,ANXA2,STC1,EXT1,PLAUR,RRAGD,ADORA2B,MT2A,SDC2,GPC1,S100A4,P4HA2,MYH9,CDKN1C,GYS1,KLF6,JMJD6,TES,ENO2,NFIL3,CYR61,AMPD3,AKAP12,MAFF,PPP1R15A,DDIT4,SCARB1,TPBG,TPST2,FOSL2
HALLMARK_TNFA_SIGNALING_VIA_NFKB%MSIGDBHALLMARK%HALLMARK_TNFA_SIGNALING_VIA_NFKB%MSIGDBHALLMARK%HALLMARK_TNFA_SIGNALING_VIA_NFKB%MSIGDBHALLMARK%HALLMARK_TNFA_SIGNALING_VIA_NFKB	HALLMARK_TNFA_SIGNALING_VIA_NFKB%MSigdbHallmark%HALLMARK_TNFA_SIGNALING_VIA_NFKB	2.23389123240488e-09	2.23389123240488e-09	1	FOSL1,IL7R,F3,FJX1,LAMB3,LIF,BTG3,CD44,ABCA1,F2RL1,TNC,SPHK1,ETS2,TNFAIP2,PLAUR,MYC,NFKB2,TRIP10,DUSP5,CSF1,RELB,KLF6,KLF10,SOCS3,NFIL3,CYR61,CLCF1,CEBPB,MAFF,PPP1R15A,PER1,TNIP2,NR4A3,FOSL2,SGK1,DENND5A,SLC2A6,RCAN1,GADD45A
EXTRACELLULAR MATRIX ORGANIZATION%GOBP%GO:0030198	extracellular matrix organization	8.4888178293053e-09	8.4888178293053e-09	1	TGFBI,COL5A1,ADAMTS7,FBN1,LOX,ADAMTSL4,TGM2,LOXL2,COL12A1,COL27A1,RECK,PHLDB2,PLOD1,PXDN,COL13A1,ADAMTS16,COL18A1,MMP24,THSD4,CRTAP,ADAMTS14,GAS6,QSOX1,MMP19,TNXB,TGFB1,COLGALT1,ADAMTS17,LOXL1,MFAP4,BMP1,CREB3L1,LOXL4,PLOD3,COL9A3,COL23A1,MYO1E,MPV17,APLP1,MMP15,FURIN,ADAMTS15
EXTERNAL ENCAPSULATING STRUCTURE ORGANIZATION%GOBP%GO:0045229	external encapsulating structure organization	8.85617802496846e-09	8.85617802496846e-09	1	TGFBI,COL5A1,ADAMTS7,FBN1,LOX,ADAMTSL4,TGM2,LOXL2,COL12A1,COL27A1,RECK,PHLDB2,PLOD1,PXDN,COL13A1,ADAMTS16,COL18A1,MMP24,THSD4,CRTAP,ADAMTS14,GAS6,QSOX1,MMP19,TNXB,TGFB1,COLGALT1,ADAMTS17,LOXL1,MFAP4,BMP1,CREB3L1,LOXL4,PLOD3,COL9A3,COL23A1,MYO1E,MPV17,APLP1,MMP15,FURIN,ADAMTS15
EXTRACELLULAR STRUCTURE ORGANIZATION%GOBP%GO:0043062	extracellular structure organization	8.85617802496846e-09	8.85617802496846e-09	1	TGFBI,COL5A1,ADAMTS7,FBN1,LOX,ADAMTSL4,TGM2,LOXL2,COL12A1,COL27A1,RECK,PHLDB2,PLOD1,PXDN,COL13A1,ADAMTS16,COL18A1,MMP24,THSD4,CRTAP,ADAMTS14,GAS6,QSOX1,MMP19,TNXB,TGFB1,COLGALT1,ADAMTS17,LOXL1,MFAP4,BMP1,CREB3L1,LOXL4,PLOD3,COL9A3,COL23A1,MYO1E,MPV17,APLP1,MMP15,FURIN,ADAMTS15
COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES%REACTOME DATABASE ID RELEASE 97%1650814	Collagen biosynthesis and modifying enzymes	3.72133588328663e-08	3.72133588328663e-08	1	COL6A1,P3H2,P3H3,COL6A2,COL5A1,COL12A1,COL27A1,PCOLCE2,PLOD1,COL13A1,COL18A1,COL6A3,P3H1,CRTAP,ADAMTS14,P4HA2,COLGALT1,BMP1,PLOD3,COL9A3,COL23A1,PPIB
ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES%REACTOME DATABASE ID RELEASE 97%2022090	Assembly of collagen fibrils and other multimeric structures	3.8327438815488e-07	3.8327438815488e-07	1	COL6A1,COL6A2,COL5A1,LOX,LAMB3,LOXL2,COL27A1,ITGB4,PXDN,COL18A1,COL6A3,LAMC2,PLEC,LOXL1,BMP1,LOXL4,CD151,COL9A3,ITGA6
BETA1 INTEGRIN CELL SURFACE INTERACTIONS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BETA1 INTEGRIN CELL SURFACE INTERACTIONS	Beta1 integrin cell surface interactions	1.18271717202093e-06	1.18271717202093e-06	1	COL6A1,COL6A2,TGFBI,COL5A1,ITGA5,FBN1,TGM2,LAMB3,TNC,LAMB1,ITGA3,COL18A1,PLAUR,COL6A3,LAMA4,LAMC2,LAMA5,PLAU,ITGA6,IGSF8
CELL MORPHOGENESIS%GOBP%GO:0000902	cell morphogenesis	1.96852548307495e-06	1.96852548307495e-06	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,EPHA2,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,STC1,TUBB3,NBL1,ROBO4,COL18A1,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,MET,ACTG1,MINK1,NTNG2,BMP7,RAC3,NFASC,MYH9,CDH2,SCN1B,SHANK3,CDH15,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SSH1,SEMA6C,MYPN,CIB1,AMOTL2,SLIT1,DOCK10,ACTN1,RAB3A,BRSK1,DVL1,ROBO3,CSPG5,CPNE1,SGK1,APLP1
NON-INTEGRIN MEMBRANE-ECM INTERACTIONS%REACTOME DATABASE ID RELEASE 97%3000171	Non-integrin membrane-ECM interactions	3.17044035669936e-06	3.17044035669936e-06	1	SNTB1,LAMB3,ITGB4,FGF2,TNC,LAMB1,LAMA4,LAMC3,SDC2,ITGB3,LAMC2,LAMA5,SNTA1,TGFB1,AGRN,HSPG2,ITGA6,ACTN1
ELASTIC FIBRE FORMATION%REACTOME DATABASE ID RELEASE 97%1566948	Elastic fibre formation	3.92633921495764e-06	3.92633921495764e-06	1	ITGA5,FBLN1,FBN1,LOX,LOXL2,ITGB3,BMP7,TGFB1,LTBP3,FBLN2,LOXL1,MFAP4,MFAP2,LOXL4,FURIN
CELL PROJECTION MORPHOGENESIS%GOBP%GO:0048858	cell projection morphogenesis	6.79993323814491e-06	6.79993323814491e-06	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,NBL1,ROBO4,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,ACTG1,MINK1,NTNG2,BMP7,RAC3,NFASC,SCN1B,SHANK3,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,DOCK10,RAB3A,BRSK1,DVL1,ROBO3,CSPG5,CPNE1,SGK1,APLP1
CELL MORPHOGENESIS INVOLVED IN NEURON DIFFERENTIATION%GOBP%GO:0048667	cell morphogenesis involved in neuron differentiation	6.79993323814491e-06	6.79993323814491e-06	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,ROBO4,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,ACTG1,MINK1,NTNG2,RAC3,NFASC,SCN1B,SHANK3,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,DOCK10,RAB3A,BRSK1,DVL1,ROBO3,APLP1
NEURON PROJECTION MORPHOGENESIS%GOBP%GO:0048812	neuron projection morphogenesis	8.01553063215045e-06	8.01553063215045e-06	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,NBL1,ROBO4,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,ACTG1,MINK1,NTNG2,BMP7,RAC3,NFASC,SCN1B,SHANK3,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,DOCK10,RAB3A,BRSK1,DVL1,ROBO3,CPNE1,SGK1,APLP1
NEURON PROJECTION DEVELOPMENT%GOBP%GO:0031175	neuron projection development	1.08992270776252e-05	1.08992270776252e-05	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,NMNAT2,EFNB3,RAB6B,UNC5A,SEMA4B,NTNG1,S100A6,RTN4RL2,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,LAMB1,TUBB3,NBL1,ROBO4,MAP7D2,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,ACTG1,MINK1,TNXB,ARTN,NTNG2,BMP7,RAC3,NFASC,SCN1B,SHANK3,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,RTN4,SLIT1,DOCK10,RAB3A,MAPT,BRSK1,DVL1,ROBO3,CSPG5,MAP4,GPRIN1,CPNE1,SGK1,APLP1,PRICKLE1,IQSEC1
PLASMA MEMBRANE BOUNDED CELL PROJECTION MORPHOGENESIS%GOBP%GO:0120039	plasma membrane bounded cell projection morphogenesis	1.08992270776252e-05	1.08992270776252e-05	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,NBL1,ROBO4,WNT5A,LRP4,MAPK8IP2,SDC2,NTN1,NPTX1,ACTG1,MINK1,NTNG2,BMP7,RAC3,NFASC,SCN1B,SHANK3,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,DOCK10,RAB3A,BRSK1,DVL1,ROBO3,CPNE1,SGK1,APLP1
POSITIVE REGULATION OF LOCOMOTION%GOBP%GO:0040017	positive regulation of locomotion	1.38557409055675e-05	1.38557409055675e-05	1	CAV1,SERPINE1,F3,TRIP6,F2R,SEMA7A,EPHA2,SEMA4B,PODXL,EGFR,FGF2,CAVIN1,SYDE1,F2RL1,TWIST1,SPHK1,LAMB1,MYLK,IGF1R,TNFRSF18,GLIPR2,WNT5A,ITGAX,CSF1,NTN1,ITGB3,ANXA1,CARMIL2,LAMC2,MET,ACTG1,GAS6,FLT1,TGFB1,PLAU,ANXA3,SLIT2,SEMA6C,PPM1F,CD151,CIB1,RTN4,ITGA6,DOCK1,PRKD1,IGSF8,SCARB1,LRRC15,PRKCE,PGF,AZU1,EMC10,NR4A3,DDRGK1,MYO1C,FAM89B,RAB40B,SMURF2,MYADM,ZP3,IQSEC1,JCAD,SNAI2
LAMININ INTERACTIONS%REACTOME DATABASE ID RELEASE 97%3000157	Laminin interactions	1.38557409055675e-05	1.38557409055675e-05	1	LAMB3,ITGB4,LAMB1,ITGA3,COL18A1,LAMA4,LAMC3,LAMC2,LAMA5,HSPG2,ITGA6
AXON DEVELOPMENT%GOBP%GO:0061564	axon development	1.38557409055675e-05	1.38557409055675e-05	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,NMNAT2,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,RTN4RL2,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,ROBO4,MAP7D2,WNT5A,NTN1,NPTX1,ACTG1,NTNG2,RAC3,NFASC,SCN1B,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,RTN4,SLIT1,RAB3A,MAPT,BRSK1,ROBO3,CSPG5,APLP1
TUBE MORPHOGENESIS%GOBP%GO:0035239	tube morphogenesis	2.13136758848507e-05	2.13136758848507e-05	1	CAV1,SERPINE1,TGFBI,ITGA5,CCBE1,LOX,WNK4,RAMP1,SOX8,LOXL2,EPHA2,DLC1,MCAM,LRP1,PODXL,RECK,ADM,FGF2,SIX2,SHH,ANXA2,PXDN,NOG,ID1,MYLK,EPAS1,ROBO4,COL18A1,MYC,EGFL7,ITGB3,TGFBR2,MET,ACTG1,MEIS3,BMP7,FLT1,TGFB1,MYH9,VASH1,JMJD6,ADGRG1,SLIT2,AMOTL2,DVL1,PGF,MTHFD1L,DLL1,PRICKLE1
RESPONSE TO HYPOXIA%GOBP%GO:0001666	response to hypoxia	2.13136758848507e-05	2.13136758848507e-05	1	CAV1,NDRG1,ANGPTL4,ADA,BNIP3,LOXL2,KCNMA1,PLOD1,TWIST1,SMAD3,EPAS1,CPEB1,MYC,AJUBA,SMAD4,BMP7,TGFB1,CBFA2T3,WTIP,PML,DDIT4,NOP53,PGF,PPARG,EGLN3,PLEKHN1,LMNA
BLOOD VESSEL MORPHOGENESIS%GOBP%GO:0048514	blood vessel morphogenesis	2.81243310734958e-05	2.81243310734958e-05	1	CAV1,SERPINE1,TGFBI,ITGA5,CCBE1,LOX,RAMP1,LOXL2,EPHA2,MCAM,LRP1,RECK,ADM,FGF2,SHH,ANXA2,PXDN,NOG,ID1,MYLK,EPAS1,ROBO4,COL18A1,EGFL7,ITGB3,TGFBR2,ACTG1,MEIS3,FLT1,TGFB1,MYH9,VASH1,JMJD6,ADGRG1,SLIT2,AMOTL2,PGF,DLL1
RESPONSE TO DECREASED OXYGEN LEVELS%GOBP%GO:0036293	response to decreased oxygen levels	3.097552387549e-05	3.097552387549e-05	1	CAV1,NDRG1,ANGPTL4,ADA,BNIP3,LOXL2,KCNMA1,PLOD1,TWIST1,SMAD3,EPAS1,CPEB1,MYC,AJUBA,SMAD4,BMP7,TGFB1,CBFA2T3,WTIP,PML,DDIT4,NOP53,PGF,PPARG,EGLN3,PLEKHN1,LMNA
POSITIVE REGULATION OF CELL MOTILITY%GOBP%GO:2000147	positive regulation of cell motility	3.57725214736859e-05	3.57725214736859e-05	1	CAV1,SERPINE1,F3,TRIP6,F2R,SEMA7A,EPHA2,SEMA4B,PODXL,EGFR,FGF2,CAVIN1,SYDE1,F2RL1,TWIST1,SPHK1,LAMB1,MYLK,IGF1R,TNFRSF18,GLIPR2,WNT5A,ITGAX,CSF1,NTN1,ITGB3,ANXA1,CARMIL2,LAMC2,MET,ACTG1,GAS6,FLT1,TGFB1,PLAU,ANXA3,SEMA6C,PPM1F,CD151,CIB1,RTN4,ITGA6,DOCK1,PRKD1,IGSF8,SCARB1,LRRC15,PRKCE,PGF,EMC10,NR4A3,DDRGK1,MYO1C,FAM89B,RAB40B,SMURF2,MYADM,ZP3,IQSEC1,JCAD,SNAI2
POSITIVE REGULATION OF CELL MIGRATION%GOBP%GO:0030335	positive regulation of cell migration	3.85622612176756e-05	3.85622612176756e-05	1	CAV1,SERPINE1,F3,TRIP6,F2R,SEMA7A,EPHA2,SEMA4B,PODXL,EGFR,FGF2,SYDE1,F2RL1,TWIST1,SPHK1,LAMB1,MYLK,IGF1R,TNFRSF18,GLIPR2,WNT5A,ITGAX,CSF1,ITGB3,ANXA1,CARMIL2,LAMC2,MET,ACTG1,GAS6,FLT1,TGFB1,PLAU,ANXA3,SEMA6C,PPM1F,CD151,CIB1,RTN4,ITGA6,DOCK1,PRKD1,IGSF8,SCARB1,LRRC15,PRKCE,PGF,EMC10,NR4A3,DDRGK1,MYO1C,FAM89B,RAB40B,SMURF2,MYADM,ZP3,IQSEC1,JCAD,SNAI2
BLOOD VESSEL DEVELOPMENT%GOBP%GO:0001568	blood vessel development	5.70570585395054e-05	5.70570585395054e-05	1	CAV1,SERPINE1,TGFBI,ITGA5,CCBE1,LOX,RAMP1,LOXL2,EPHA2,MCAM,LRP1,RECK,ADM,FGF2,SHH,ANXA2,PXDN,NOG,ID1,MYLK,EPAS1,ROBO4,COL18A1,EGFL7,ITGB3,PDE2A,TGFBR2,ACTG1,MEIS3,FLT1,TGFB1,MYH9,VASH1,APLN,JMJD6,ADGRG1,SLIT2,AMOTL2,PGF,DLL1
AXONOGENESIS%GOBP%GO:0007409	axonogenesis	7.44120341351533e-05	7.44120341351533e-05	1	ADGRB1,DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,NTNG1,S100A6,KLF7,TENM2,EPHA8,BRSK2,KIAA1755,SHH,TENM3,TUBB3,ROBO4,WNT5A,NTN1,NPTX1,ACTG1,NTNG2,RAC3,NFASC,SCN1B,SLIT3,MAP1B,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,RAB3A,BRSK1,ROBO3,APLP1
RESPONSE TO OXYGEN LEVELS%GOBP%GO:0070482	response to oxygen levels	7.44120341351533e-05	7.44120341351533e-05	1	CAV1,NDRG1,ANGPTL4,ADA,BNIP3,LOXL2,KCNMA1,PLOD1,TWIST1,SMAD3,EPAS1,CPEB1,MYC,AJUBA,SMAD4,BMP7,TGFB1,ATG7,CBFA2T3,WTIP,PML,DDIT4,NOP53,PGF,PPARG,EGLN3,PLEKHN1,LMNA
VASCULATURE DEVELOPMENT%GOBP%GO:0001944	vasculature development	8.26951818721992e-05	8.26951818721992e-05	1	CAV1,SERPINE1,TGFBI,ITGA5,CCBE1,LOX,ERRFI1,RAMP1,LOXL2,EPHA2,MCAM,LRP1,RECK,ADM,FGF2,SHH,ANXA2,PXDN,NOG,ID1,MYLK,EPAS1,ROBO4,COL18A1,EGFL7,ITGB3,PDE2A,TGFBR2,ACTG1,MEIS3,FLT1,TGFB1,MYH9,VASH1,APLN,JMJD6,ADGRG1,SLIT2,AMOTL2,PGF,DLL1
HALLMARK_IL2_STAT5_SIGNALING%MSIGDBHALLMARK%HALLMARK_IL2_STAT5_SIGNALING%MSIGDBHALLMARK%HALLMARK_IL2_STAT5_SIGNALING%MSIGDBHALLMARK%HALLMARK_IL2_STAT5_SIGNALING	HALLMARK_IL2_STAT5_SIGNALING%MSigdbHallmark%HALLMARK_IL2_STAT5_SIGNALING	0.000125992123968487	0.000125992123968487	1	COL6A1,LIF,CD44,NT5E,IFITM3,IGF1R,TNFRSF18,GLIPR2,RRAGD,MYC,CSF1,PLAGL1,NCS1,GABARAPL1,PLEC,ADAM19,SPRY4,CDKN1C,KLF6,SOCS2,NFIL3,ITGA6,GPX4,MAFF,MYO1E,MYO1C,APLP1,DENND5A,DHRS3,FURIN
ANGIOGENESIS%GOBP%GO:0001525	angiogenesis	0.000129884743926616	0.000129884743926616	1	SERPINE1,TGFBI,ITGA5,CCBE1,RAMP1,LOXL2,EPHA2,MCAM,RECK,FGF2,SHH,ANXA2,PXDN,ID1,EPAS1,ROBO4,COL18A1,ITGB3,TGFBR2,ACTG1,MEIS3,FLT1,TGFB1,MYH9,VASH1,JMJD6,ADGRG1,SLIT2,AMOTL2,PGF,DLL1
TUBE DEVELOPMENT%GOBP%GO:0035295	tube development	0.000163454356123183	0.000163454356123183	1	CAV1,SERPINE1,TGFBI,ITGA5,CCBE1,LOX,WNK4,ERRFI1,RAMP1,CLMP,SOX8,LOXL2,EPHA2,DLC1,MCAM,LRP1,PODXL,RECK,ADM,FGF2,PKDCC,SIX2,SHH,ANXA2,PXDN,NOG,ID1,MYLK,EPAS1,ITGA3,ROBO4,COL18A1,MYC,EGFL7,ITGB3,TGFBR2,MET,ACTG1,MEIS3,BMP7,FLT1,TGFB1,MYH9,VASH1,JMJD6,ADGRG1,SLIT2,AMOTL2,DVL1,PGF,MTHFD1L,DLL1,PRICKLE1
REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION%GOBP%GO:1903053	regulation of extracellular matrix organization	0.000188264615734933	0.000188264615734933	1	LRP1,RECK,LAMB1,SMAD3,FSCN1,PLAUR,ZNF469,CARMIL2,SMAD4,TNXB,TGFB1,COLGALT1,PLAU,MELTF,PPARG
INTEGRIN SIGNALLING PATHWAY%PANTHER PATHWAY%P00034	Integrin signalling pathway	0.000233608841958223	0.000233608841958223	1	CAV1,COL6A1,COL6A2,COL5A1,ITGA5,LAMB3,ARHGAP26,COL12A1,COL27A1,ITGB4,LAMB1,ITGA3,COL13A1,PARVB,ITGAX,COL6A3,LAMA4,LAMC3,FLNB,LAMC2,LAMA5,ACTG1,COL9A3,ITGA6,ACTN1,DOCK1,ITGB2,MAP3K3
REGULATION OF PLASMA MEMBRANE BOUNDED CELL PROJECTION ORGANIZATION%GOBP%GO:0120035	regulation of plasma membrane bounded cell projection organization	0.000246381912836006	0.000246381912836006	1	CAV1,DPYSL5,L1CAM,SEMA7A,EFNB3,CDC42EP3,EPHA2,PODXL,CD44,NTNG1,RTN4RL2,TENM2,NOVA2,SPOCK1,F2RL1,BRSK2,TENM3,FSCN1,NGEF,ITM2C,WNT5A,LRP4,P3H1,DBN1,SDC2,NTN1,CARMIL2,NCS1,KIF1A,CORO1C,NTNG2,BMP7,CDH2,SCN1B,SHANK3,PALM,CDC42EP1,SLIT2,CIB1,RTN4,ITGA6,CCDC88A,PRKD1,LIMK1,MAPT,BRSK1,KCTD17,MAP4,CAMK1,BRK1,KIF26A,RAB40B,MACF1,ACAP3,DENND5A,EPS8L2
POSITIVE REGULATION OF EXTRACELLULAR MATRIX ORGANIZATION%GOBP%GO:1903055	positive regulation of extracellular matrix organization	0.000249199698895857	0.000249199698895857	1	SMAD3,FSCN1,PLAUR,CARMIL2,SMAD4,TNXB,TGFB1,COLGALT1,PLAU,MELTF
REGULATION OF NEURON PROJECTION DEVELOPMENT%GOBP%GO:0010975	regulation of neuron projection development	0.000267222858593919	0.000267222858593919	1	DPYSL5,L1CAM,SEMA7A,EFNB3,NTNG1,RTN4RL2,NOVA2,SPOCK1,BRSK2,TENM3,NGEF,ITM2C,WNT5A,LRP4,P3H1,DBN1,SDC2,NTN1,NCS1,KIF1A,NTNG2,BMP7,CDH2,SCN1B,SHANK3,SLIT2,CIB1,RTN4,ITGA6,CCDC88A,PRKD1,LIMK1,MAPT,BRSK1,CAMK1,KIF26A,MACF1,ACAP3,DENND5A
REGULATION OF CELL PROJECTION ORGANIZATION%GOBP%GO:0031344	regulation of cell projection organization	0.00027015208377229	0.00027015208377229	1	CAV1,DPYSL5,L1CAM,SEMA7A,EFNB3,CDC42EP3,EPHA2,PODXL,CD44,NTNG1,RTN4RL2,TENM2,NOVA2,SPOCK1,F2RL1,BRSK2,TENM3,FSCN1,NGEF,ITM2C,WNT5A,LRP4,P3H1,DBN1,SDC2,NTN1,CARMIL2,NCS1,KIF1A,CORO1C,NTNG2,BMP7,CDH2,SCN1B,SHANK3,PALM,CDC42EP1,SLIT2,CIB1,RTN4,ITGA6,CCDC88A,PRKD1,LIMK1,MAPT,BRSK1,KCTD17,DVL1,MAP4,CAMK1,BRK1,KIF26A,RAB40B,MACF1,ACAP3,DENND5A,EPS8L2
TISSUE MORPHOGENESIS%GOBP%GO:0048729	tissue morphogenesis	0.000361693892532334	0.000361693892532334	1	COL5A1,ITGA5,WNK4,SOX8,HMGA2,EPHA2,DLC1,PODXL,CD44,ITGB4,FGF2,BRSK2,SIX2,SHH,STC1,NOG,MYLK,ITGA3,WNT5A,MYC,KRT16,ITGB3,TGFBR2,CARMIL2,SMAD4,MET,ACTG1,BMP7,KRT17,TGFB1,WNT10A,SLIT2,CD151,BRSK1,RIPK4,DVL1,MTHFD1L,DLL1,AHDC1,EYA2,PRICKLE1,SNAI2
AXON GUIDANCE%GOBP%GO:0007411	axon guidance	0.000396062515684361	0.000396062515684361	1	DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,KLF7,TENM2,EPHA8,KIAA1755,SHH,TENM3,TUBB3,ROBO4,WNT5A,NTN1,RAC3,NFASC,SCN1B,SLIT3,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,ROBO3
HIPPO MERLIN SIGNALING DYSREGULATION%WIKIPATHWAYS_20260910%WP4541%HOMO SAPIENS	Hippo Merlin signaling dysregulation	0.000406307028452995	0.000406307028452995	1	CTGF,EPHA2,CD44,ITGB4,EGFR,IGF1R,ITGAX,MYC,AJUBA,ITGB3,FLT1,CDH2,CDH15,TEAD4,NF2,ITGA6,NGFR,PRKAR1B
NEURON PROJECTION GUIDANCE%GOBP%GO:0097485	neuron projection guidance	0.000427965089262817	0.000427965089262817	1	DPYSL5,L1CAM,SEMA7A,EFNB3,UNC5A,SEMA4B,KLF7,TENM2,EPHA8,KIAA1755,SHH,TENM3,TUBB3,ROBO4,WNT5A,NTN1,RAC3,NFASC,SCN1B,SLIT3,BOC,PTPRH,SLIT2,SEMA6C,MYPN,SLIT1,ROBO3
1P36 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5345%HOMO SAPIENS	1p36 copy number variation syndrome	0.000452751583508094	0.000452751583508094	1	TNFRSF18,LRP4,SMAD4,ATAD3C,TGFB1,AGRN,KLHL17,ISG15,PRKCZ,NADK,TMEM52,DVL1,PLCH2,PEX10,PUSL1,SCNN1D,ACAP3,PLEKHN1,ATAD3A
COLLAGEN FIBRIL ORGANIZATION%GOBP%GO:0030199	collagen fibril organization	0.000652286400140868	0.000652286400140868	1	COL5A1,FBN1,LOX,LOXL2,COL12A1,PLOD1,PXDN,CRTAP,ADAMTS14,COLGALT1,LOXL1,BMP1,LOXL4,PLOD3
TYPE I HEMIDESMOSOME ASSEMBLY%REACTOME DATABASE ID RELEASE 97%446107	Type I hemidesmosome assembly	0.000738657177994977	0.000738657177994977	1	LAMB3,ITGB4,LAMC2,PLEC,CD151,ITGA6
DISSOLUTION OF FIBRIN CLOT%REACTOME DATABASE ID RELEASE 97%75205	Dissolution of Fibrin Clot	0.000766416040499341	0.000766416040499341	1	SERPINE1,SERPINE2,ANXA2,PLAUR,PLAU,PLAT,S100A10
REGULATION OF CELL-SUBSTRATE ADHESION%GOBP%GO:0010810	regulation of cell-substrate adhesion	0.000898652100994308	0.000898652100994308	1	SERPINE1,CORO2B,FBLN1,DLC1,SPOCK1,AJAP1,PHLDB2,CSF1,ACTG1,MINK1,CORO1C,RAC3,SPRY4,FBLN2,PLAU,NF2,PPM1F,CIB1,S100A10,CDKN2A,DOCK1,MELTF,PLEKHA2,CSPG5,DAPK3,MACF1,MYADM,IQSEC1
MET ACTIVATES PTK2 SIGNALING%REACTOME DATABASE ID RELEASE 97%8874081	MET activates PTK2 signaling	0.000898652100994308	0.000898652100994308	1	LAMB3,LAMB1,ITGA3,LAMA4,LAMC3,LAMC2,LAMA5,MET
REGULATION OF PLASMINOGEN ACTIVATION%GOBP%GO:0010755	regulation of plasminogen activation	0.000898652100994308	0.000898652100994308	1	SERPINE1,SERPINE2,ANXA2,PLAUR,PLAU,PLAT,S100A10,MELTF
ECM PROTEOGLYCANS%REACTOME DATABASE ID RELEASE 97%3000178	ECM proteoglycans	0.000921464399235817	0.000921464399235817	1	SERPINE1,BGN,TNC,LAMB1,ITGAX,LRP4,LAMA4,ITGB3,LAMA5,TNXB,TGFB1,AGRN,HSPG2,COL9A3
EMBRYONIC MORPHOGENESIS%GOBP%GO:0048598	embryonic morphogenesis	0.00106332907963266	0.00106332907963266	1	COL6A1,ITGA5,FBN1,SOX8,LAMB3,HMGA2,COL12A1,DLC1,ALDH1A3,ITGB4,FGF2,HOXB9,DUSP1,SIX2,SHH,NOG,TWIST1,LAMB1,ITGA3,WNT5A,DUSP5,ITGB3,TGFBR2,BMP7,FLT1,TGFB1,MFAP2,DVL1,ECE1,MTHFD1L,DLL1,AHDC1,NR4A3,ITGB2,EYA2,PRICKLE1,CYP26B1,MMP15
ENDOCYTOSIS%GOBP%GO:0006897	endocytosis	0.00106332907963266	0.00106332907963266	1	CAV1,AXL,ADGRB1,BIN1,EHD2,MRC2,DNER,RAMP1,SRPX,TGM2,CAV2,LRP1,CD44,ADM,PDLIM7,DNM1,SNCG,ITGAX,ITGB3,ANXA1,SH3GL3,GRK3,SNX33,GAS6,CORO1C,MYH9,HSPG2,ANXA3,CLTCL1,JMJD6,TPCN2,HIP1,DOCK1,LIMK1,DENND1A,FCHO1,SCARB1,PRKCE,MYO1E,DLL1,ITGB2,MAPKAPK3,MYO1C,RABEPK,SH3GL1,HGS
HALLMARK_UV_RESPONSE_DN%MSIGDBHALLMARK%HALLMARK_UV_RESPONSE_DN%MSIGDBHALLMARK%HALLMARK_UV_RESPONSE_DN%MSIGDBHALLMARK%HALLMARK_UV_RESPONSE_DN	HALLMARK_UV_RESPONSE_DN%MSigdbHallmark%HALLMARK_UV_RESPONSE_DN	0.00106332907963266	0.00106332907963266	1	F3,FHL2,ANXA2,KCNMA1,ID1,IGF1R,ADORA2B,MYC,GRK5,SDC2,ITGB3,TGFBR2,MAP1B,CYR61,SCN8A,FZD2,PRKCE,PPARG,MAP2K5,GCNT1,SNAI2
REGULATION OF PROTEIN PROCESSING%GOBP%GO:0070613	regulation of protein processing	0.00106790433715241	0.00106790433715241	1	SERPINE1,CCBE1,NKD2,SERPINE2,ANXA2,PLAUR,GAS1,MYH9,PLAU,PLAT,S100A10,MELTF
FORMATION OF THE DYSTROPHIN-GLYCOPROTEIN COMPLEX (DGC)%REACTOME DATABASE ID RELEASE 97%9913351	Formation of the dystrophin-glycoprotein complex (DGC)	0.00106790433715241	0.00106790433715241	1	SNTB1,LAMB3,LAMB1,LAMA4,LAMC3,LAMC2,LAMA5,SNTA1,AGRN,HSPG2
FORMATION OF PRIMARY GERM LAYER%GOBP%GO:0001704	formation of primary germ layer	0.00106790433715241	0.00106790433715241	1	COL6A1,ITGA5,LAMB3,HMGA2,COL12A1,ITGB4,DUSP1,SIX2,LAMB1,ITGA3,DUSP5,ITGB3,AHDC1,ITGB2,EYA2,MMP15
BETA3 INTEGRIN CELL SURFACE INTERACTIONS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BETA3 INTEGRIN CELL SURFACE INTERACTIONS	Beta3 integrin cell surface interactions	0.00106790433715241	0.00106790433715241	1	TGFBI,FBN1,L1CAM,TNC,SPHK1,LAMB1,PLAUR,LAMA4,ITGB3,TGFBR2,PVR,PLAU
REGULATION OF NERVOUS SYSTEM DEVELOPMENT%GOBP%GO:0051960	regulation of nervous system development	0.00106790433715241	0.00106790433715241	1	DPYSL5,BIN1,L1CAM,SEMA7A,SERPINE2,TGM2,EFNB3,SOX8,SMARCD3,NOG,ITGAX,SYNDIG1,LRP4,DBN1,CNTFR,NTN1,CDK18,TGFB1,CDH2,AGRN,SHANK3,RASSF10,NF2,SLIT2,RTN4,NUMBL,CLCF1,SLIT1,LIMK1,MAPT,RGS14,NLGN2,DLL1,MACF1
CELL-SUBSTRATE ADHESION%GOBP%GO:0031589	cell-substrate adhesion	0.00106790433715241	0.00106790433715241	1	CORO2B,TRIP6,ITGA5,L1CAM,LAMB3,DLC1,CD44,ITGB4,MSLN,LAMB1,ZYX,ITGA3,COL13A1,PARVB,PLAUR,ITGAX,LAMC3,ITGB3,LAMA5,RSU1,ITGA6,MSLNL,ACTN1,THSD1,ITGB2
INTEGRIN CELL SURFACE INTERACTIONS%REACTOME%R-HSA-216083.6	Integrin cell surface interactions	0.00106790433715241	0.00106790433715241	1	ITGA5,FBN1,CD44,TNC,ITGA3,COL13A1,COL18A1,ITGAX,ITGB3,AGRN,HSPG2,COL9A3,ITGA6,COL23A1,ITGB2
ACTIN CYTOSKELETON ORGANIZATION%GOBP%GO:0030036	actin cytoskeleton organization	0.0011381397406952	0.0011381397406952	1	CORO2B,LIX1L,FAM171A1,ARHGAP26,DLC1,ELMO3,PDLIM7,SYDE1,BRSK2,FHOD3,ZYX,PARVB,FSCN1,WIPF1,EHBP1L1,SH3D21,DBN1,TNNT1,TRIP10,WIPF3,CNN2,ANXA1,FLNB,CARMIL2,EFHD2,MINK1,CORO1C,TNXB,NUAK2,RAC3,MYH9,SPTBN1,FHL3,KLHL17,LIMD2,RHOF,NF2,SSH1,MYPN,AMOTL2,HIP1,ACTN1,LIMK1,CNP,MYO1E,RFLNB,MAD2L2,FLII,TPM2,MYO1C,SPECC1,SH3KBP1,ACAP3,PDLIM2,SH3BP4
HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK	HIF-1-alpha transcription factor network	0.00124043951464481	0.00124043951464481	1	SERPINE1,CA9,PLIN2,NDRG1,BNIP3,NT5E,ADM,SMAD3,SMAD4,LDHA,PFKFB3,ITGB2,EGLN3,SLC2A1,FURIN
CROSSLINKING OF COLLAGEN FIBRILS%REACTOME DATABASE ID RELEASE 97%2243919	Crosslinking of collagen fibrils	0.00127263599440033	0.00127263599440033	1	LOX,LOXL2,PXDN,LOXL1,BMP1,LOXL4
HALLMARK_APICAL_JUNCTION%MSIGDBHALLMARK%HALLMARK_APICAL_JUNCTION%MSIGDBHALLMARK%HALLMARK_APICAL_JUNCTION%MSIGDBHALLMARK%HALLMARK_APICAL_JUNCTION	HALLMARK_APICAL_JUNCTION%MSigdbHallmark%HALLMARK_APICAL_JUNCTION	0.00141289504084244	0.00141289504084244	1	TGFBI,FBN1,WNK4,CALB2,LAMB3,GNAI1,ITGB4,EGFR,ZYX,CNN2,LAMC2,ACTG1,TSPAN4,MYH9,CDH15,BMP1,ADRA1B,RHOF,NF2,SLIT2,RSU1,SPEG,ACTN1,ADAM23,NLGN2,SIRPA
CELL JUNCTION ORGANIZATION%GOBP%GO:0034330	cell junction organization	0.00149499639374101	0.00149499639374101	1	CORO2B,TRIP6,F2R,L1CAM,DNER,GJB2,ELFN1,DLC1,C3,ITGB4,NTNG1,TENM2,F2RL1,TENM3,IGF1R,SMAD3,PLXNA2,ITGA3,FSCN1,SNCG,KIFC3,C1QL1,WNT5A,LRP4,ACTG1,NTNG2,PLEC,RAC3,TGFB1,CDH2,AGRN,SHANK3,CDH15,PPFIA4,PALM,SDK2,LRFN4,ITGA6,DOCK10,ACTN1,THSD1,MAPT,PRTN3,DVL1,NLGN2,PCDHGC5,SNAI2,BSN
REGULATION OF PROTEIN MATURATION%GOBP%GO:1903317	regulation of protein maturation	0.00162244289974661	0.00162244289974661	1	SERPINE1,CCBE1,NKD2,SERPINE2,ANXA2,PLAUR,GAS1,MYH9,PLAU,PLAT,S100A10,MELTF
DEGRADATION OF THE EXTRACELLULAR MATRIX%REACTOME%R-HSA-1474228.6	Degradation of the extracellular matrix	0.00170082115860219	0.00170082115860219	1	TIMP2,LAMB3,COL12A1,CD44,HTRA1,TIMP1,LAMB1,COL13A1,ADAMTS16,COL18A1,MMP24,LAMC2,LAMA5,MMP19,HSPG2,BMP1,COL9A3,COL23A1,MMP15,FURIN
SYNDECAN INTERACTIONS%REACTOME%R-HSA-3000170.4	Syndecan interactions	0.00170082115860219	0.00170082115860219	1	ITGB4,FGF2,TNC,SDC2,ITGB3,TGFB1,ITGA6,ACTN1
CANONICAL AND NON CANONICAL TGF B SIGNALING%WIKIPATHWAYS_20260910%WP3874%HOMO SAPIENS	Canonical and non canonical TGF B signaling	0.00175292393399481	0.00175292393399481	1	LOXL2,TGFBR2,SMAD4,TGFB1,LOXL1,BMP1,LOXL4
REGULATION OF GROWTH%GOBP%GO:0040008	regulation of growth	0.00176099025226972	0.00176099025226972	1	L1CAM,SEMA7A,FHL1,GNG4,EGFR,FGF2,SPOCK1,TNC,NOG,SPHK1,RNF157,SMAD3,MT2A,NTN1,SMAD4,TGFB1,CDH2,AGRN,SIPA1,SLIT3,SOCS2,SLIT2,PPM1F,CIB1,RTN4,PML,DACT3,DCBLD2,CDKN2A,LIMK1,MAPT,SPHK2,PPIB,CCDC85B,NPR1,BASP1,MAD2L2,DLL1,OGFR,KIF26A,IL17RA,MACF1,ZP3,SH3BP4,ATAD3A
SPLICING FACTOR NOVA REGULATED SYNAPTIC PROTEINS%WIKIPATHWAYS_20260910%WP4148%HOMO SAPIENS	Splicing factor NOVA regulated synaptic proteins	0.00176099025226972	0.00176099025226972	1	CAV2,NTNG1,KCNMA1,GABBR2,CDH2,AGRN,PRKCZ,MAP4,CADM1,STX2
REGULATION OF G PROTEIN-COUPLED RECEPTOR SIGNALING PATHWAY%GOBP%GO:0008277	regulation of G protein-coupled receptor signaling pathway	0.00182439009918607	0.00182439009918607	1	SERPINE1,ADA,GNAI1,CAV2,GNG4,C3,ADM,SH2B3,GRK5,PDE2A,SLC39A14,GRK3,PALM,SLIT3,APLN,SLIT2,RGS19,NMT2,PRKD1,NECAB2,RGS14,APLP1,GIT1
VALIDATED TRANSCRIPTIONAL TARGETS OF TAP63 ISOFORMS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%VALIDATED TRANSCRIPTIONAL TARGETS OF TAP63 ISOFORMS	Validated transcriptional targets of TAp63 isoforms	0.00215902412039335	0.00215902412039335	1	ADA,ITGB4,MFGE8,SHH,SMARCD3,ITGA3,S100A2,PML,CDKN2A,OGG1,AEN,DHRS3,GADD45A
ALPHA6 BETA4 INTEGRIN-LIGAND INTERACTIONS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%ALPHA6 BETA4 INTEGRIN-LIGAND INTERACTIONS	Alpha6 beta4 integrin-ligand interactions	0.00227421553804835	0.00227421553804835	1	LAMB3,ITGB4,LAMB1,LAMC2,LAMA5,ITGA6
REGULATION OF EXTRACELLULAR MATRIX DISASSEMBLY%GOBP%GO:0010715	regulation of extracellular matrix disassembly	0.00235854906825988	0.00235854906825988	1	LRP1,RECK,FSCN1,PLAUR,CARMIL2,TGFB1,PLAU,MELTF
GASTRULATION%GOBP%GO:0007369	gastrulation	0.00262364717589645	0.00262364717589645	1	COL6A1,ITGA5,LAMB3,HMGA2,COL12A1,ITGB4,DUSP1,SIX2,LAMB1,ITGA3,DUSP5,ITGB3,AHDC1,NR4A3,ITGB2,EYA2,MMP15
REGULATION OF NEUROGENESIS%GOBP%GO:0050767	regulation of neurogenesis	0.00263347742395059	0.00263347742395059	1	DPYSL5,BIN1,L1CAM,SEMA7A,SERPINE2,TGM2,EFNB3,SOX8,SMARCD3,NOG,LRP4,DBN1,CNTFR,NTN1,TGFB1,CDH2,SHANK3,RASSF10,NF2,SLIT2,RTN4,NUMBL,CLCF1,LIMK1,MAPT,RGS14,DLL1,MACF1
REGULATION OF ACTIN FILAMENT-BASED PROCESS%GOBP%GO:0032970	regulation of actin filament-based process	0.00265424846247418	0.00265424846247418	1	CAV1,CORO2B,BIN1,CSF3,CDC42EP3,DLC1,LRP1,F2RL1,FHOD3,PHLDB2,STC1,FSCN1,NGEF,COTL1,TRIP10,CNN2,HCN4,CARMIL2,SMAD4,ACTG1,RAC3,MYH9,SHANK3,ARAP3,CDC42EP1,RHOF,NF2,SLIT2,SSH1,PPM1F,SCN5A,S100A10,CCDC88A,LIMK1,PRKCE,DAPK3,FLII,BRK1,RAB40B,MYADM
RESPONSE TO WOUNDING%GOBP%GO:0009611	response to wounding	0.00277709913871947	0.00277709913871947	1	AXL,F3,COL5A1,ITGA5,F2R,FBLN1,MCAM,THBD,CD44,ITGB4,FGF2,RTN4RL2,TNC,RASA3,NOG,SMAD3,PLAUR,WNT5A,SAA1,ITGB3,CARMIL2,ACTG1,UBASH3B,PLEC,TGFB1,MYH9,VASH1,DGKD,CD151,PLAT,DCBLD2,RAB3A,PABPC4,SCARB1,CSPG5,ZFP36L2,MACF1
POST-TRANSLATIONAL PROTEIN PHOSPHORYLATION%REACTOME DATABASE ID RELEASE 97%8957275	Post-translational protein phosphorylation	0.00281723108599071	0.00281723108599071	1	FBN1,SERPINA1,C3,MFGE8,MSLN,TNC,TIMP1,LGALS1,LAMB1,FSTL3,FAM20C,CSF1,SDC2,GAS6,QSOX1,CDH2,GOLM1,RCN1,MELTF
REGULATION OF CELL ADHESION MEDIATED BY INTEGRIN%GOBP%GO:0033628	regulation of cell adhesion mediated by integrin	0.00281723108599071	0.00281723108599071	1	SERPINE1,ADA,TESC,LIF,EPHA2,PODXL,EPHA8,RAC3,PLAU,CIB1,SNAI2
MORPHOGENESIS OF AN EPITHELIUM%GOBP%GO:0002009	morphogenesis of an epithelium	0.00281723108599071	0.00281723108599071	1	COL5A1,ITGA5,WNK4,SOX8,EPHA2,DLC1,PODXL,CD44,FGF2,BRSK2,SIX2,SHH,WNT5A,MYC,KRT16,ITGB3,TGFBR2,CARMIL2,MET,ACTG1,BMP7,KRT17,TGFB1,WNT10A,SLIT2,CD151,BRSK1,RIPK4,DVL1,MTHFD1L,DLL1,PRICKLE1
CELL-MATRIX ADHESION%GOBP%GO:0007160	cell-matrix adhesion	0.00281723108599071	0.00281723108599071	1	CORO2B,TRIP6,ITGA5,L1CAM,DLC1,CD44,ITGB4,MSLN,ZYX,ITGA3,COL13A1,PLAUR,ITGAX,ITGB3,RSU1,ITGA6,MSLNL,ACTN1,THSD1,ITGB2
POSITIVE REGULATION OF NERVOUS SYSTEM DEVELOPMENT%GOBP%GO:0051962	positive regulation of nervous system development	0.00281723108599071	0.00281723108599071	1	BIN1,L1CAM,SEMA7A,SERPINE2,TGM2,SOX8,SMARCD3,SYNDIG1,DBN1,NTN1,TGFB1,CDH2,AGRN,SHANK3,RASSF10,SLIT2,NUMBL,CLCF1,LIMK1,MAPT,RGS14,NLGN2,MACF1
POSITIVE REGULATION OF NEUROGENESIS%GOBP%GO:0050769	positive regulation of neurogenesis	0.00305372034099077	0.00305372034099077	1	BIN1,L1CAM,SEMA7A,SERPINE2,TGM2,SOX8,SMARCD3,DBN1,NTN1,TGFB1,CDH2,SHANK3,RASSF10,SLIT2,NUMBL,CLCF1,LIMK1,MAPT,RGS14,MACF1
REGULATION OF CELL GROWTH%GOBP%GO:0001558	regulation of cell growth	0.00346621225769999	0.00346621225769999	1	L1CAM,SEMA7A,FHL1,GNG4,EGFR,SPOCK1,TNC,SPHK1,RNF157,SMAD3,NTN1,SMAD4,TGFB1,CDH2,SIPA1,SLIT3,SOCS2,SLIT2,CIB1,RTN4,PML,DACT3,DCBLD2,CDKN2A,LIMK1,MAPT,SPHK2,CCDC85B,NPR1,MAD2L2,OGFR,KIF26A,IL17RA,MACF1,SH3BP4,ATAD3A
UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) AND UPAR-MEDIATED SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA) AND UPAR-MEDIATED SIGNALING	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling	0.00346621225769999	0.00346621225769999	1	SERPINE1,ITGA5,LRP1,EGFR,ITGA3,PLAUR,ITGB3,TGFB1,PLAU,DOCK1,ITGB2
REGULATION OF TRANSMEMBRANE TRANSPORT%GOBP%GO:0034762	regulation of transmembrane transport	0.00381397410867741	0.00381397410867741	1	CAV1,BIN1,F2R,FXYD5,TESC,FHL1,C3,PID1,IRS2,SLC8A1,KCNAB2,STAC2,KCNH2,KCNG1,PRKAG2,MINK1,UBASH3B,CBARP,SNTA1,SCN1B,KCNIP3,CLTCL1,JPH2,PML,SCN5A,SLC26A6,KCNS3,ERFE,SPHK2,WNK2,PRKCE,CRACR2A,ADAM23,P2RX5,NR4A3,JPH3,TMEM38A,PEA15
REGULATION OF LIPID LOCALIZATION%GOBP%GO:1905952	regulation of lipid localization	0.00392278464182524	0.00392278464182524	1	CAV1,PLIN2,ANGPTL4,LRP1,C3,ABCA1,C1QTNF1,SHH,ANXA2,IRS2,GPIHBP1,ZDHHC8,ITGB3,GAL,PLIN3,TSPO,PLTP,NMB,SCARB1,PPARG,ABCA2
ADIPOGENESIS%WIKIPATHWAYS_20260910%WP236%HOMO SAPIENS	Adipogenesis	0.00392278464182524	0.00392278464182524	1	LIF,NR2F1,KLF7,SPOCK1,TWIST1,CNTFR,ID3,WNT10B,TGFB1,BMP1,KLF6,SOCS3,CEBPB,DVL1,HMGA1,PPARG,CYP26B1,GADD45A,LMNA
DEVELOPMENTAL CELL LINEAGES%REACTOME DATABASE ID RELEASE 97%9734767	Developmental Cell Lineages	0.00422094309673671	0.00422094309673671	1	LAMB3,FGF2,LAMB1,CSF1,LAMA4,LAMC3,LAMC2,LAMA5
NEGATIVE REGULATION OF CELL ADHESION%GOBP%GO:0007162	negative regulation of cell adhesion	0.00458786332653681	0.00458786332653681	1	SERPINE1,CORO2B,TGFBI,FXYD5,FBLN1,SERPINE2,EPHA2,DLC1,PODXL,SPOCK1,C1QTNF1,AJAP1,DUSP1,PHLDB2,LGALS1,SH2B3,AKNA,ANXA1,CORO1C,TGFB1,SPRY4,SIPA1,NF2,PPM1F,CDKN2A,CEBPB,MELTF,PSMA7,MAD2L2,JAK3,MAP2K5,MYADM,SNAI2
HALLMARK_GLYCOLYSIS%MSIGDBHALLMARK%HALLMARK_GLYCOLYSIS%MSIGDBHALLMARK%HALLMARK_GLYCOLYSIS%MSIGDBHALLMARK%HALLMARK_GLYCOLYSIS	HALLMARK_GLYCOLYSIS%MSigdbHallmark%HALLMARK_GLYCOLYSIS	0.0047578520869696	0.0047578520869696	1	TGFBI,ANGPTL4,CD44,EGFR,NT5E,DPYSL4,PLOD1,STC1,EXT1,RRAGD,ADORA2B,SDC2,GPC1,SPAG4,ARTN,P4HA2,AGRN,GYS1,ENO2,DDIT4,CHPF2,TPBG,EGLN3,ME2,CACNA1H
SKELETAL SYSTEM DEVELOPMENT%GOBP%GO:0001501	skeletal system development	0.00510946161491715	0.00510946161491715	1	COL5A1,FBN1,TGM2,NFATC2,HMGA2,COL27A1,CD44,FGF2,PKDCC,HOXB9,ANXA2,STC1,NOG,TWIST1,ETS2,COL13A1,COL18A1,WNT5A,P3H1,TGFBR2,LAMA5,SLC39A14,BMP7,WNT10B,TGFB1,HAPLN3,BMP1,TEAD4,GPR161,PPIB,P2RX5,RFLNB,MTHFD1L,DDRGK1,CYP26B1
VEGFA VEGFR2 SIGNALING%WIKIPATHWAYS_20260910%WP3888%HOMO SAPIENS	VEGFA VEGFR2 signaling	0.00514189717056544	0.00514189717056544	1	F3,FHL2,BIN1,FJX1,CTGF,NFATC2,EPHA2,HTRA1,SLC8A1,SH3BGRL3,PLAUR,MAPK12,DUSP5,ITGB3,GPC1,ANXA1,FLNB,ACTG1,SHC2,FLT1,P4HA2,MYH9,TEAD4,TNFRSF10C,SHB,PLOD3,PRKCZ,CYR61,PRKD1,LIMK1,CNP,PRKCE,TMSB10,FLII,NR4A3,MYO1C,LRRFIP2,SND1,PLCB3,RCAN1,HGS
WOUND HEALING%GOBP%GO:0042060	wound healing	0.00515922875711256	0.00515922875711256	1	AXL,F3,COL5A1,ITGA5,F2R,FBLN1,MCAM,THBD,CD44,FGF2,RASA3,NOG,SMAD3,PLAUR,WNT5A,SAA1,ITGB3,CARMIL2,ACTG1,UBASH3B,PLEC,TGFB1,MYH9,DGKD,CD151,PLAT,DCBLD2,RAB3A,PABPC4,SCARB1,MACF1
2Q37 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5224%HOMO SAPIENS	2q37 copy number variation syndrome	0.00522445487311644	0.00522445487311644	1	RAMP1,EGFR,ABCA1,RRAGD,ITGB3,GPC1,GABARAPL1,KIF1A,ANO7,GYS1,DGKD,THAP4,ERFE,ARL4C,COPS9,MAP4,SNED1,BOK,SH3BP4
PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260910%WP98%HOMO SAPIENS	Prostaglandin synthesis and regulation	0.00522445487311644	0.00522445487311644	1	PTGIR,S100A6,ANXA2,ANXA1,PTGES,ANXA3,TBXA2R,S100A10,PPARG,ANXA6
DEVELOPMENTAL CELL LINEAGES OF THE EXOCRINE PANCREAS%REACTOME DATABASE ID RELEASE 97%9820448	Developmental Cell Lineages of the Exocrine Pancreas	0.00522445487311644	0.00522445487311644	1	LAMB3,FGF2,LAMB1,LAMA4,LAMC3,LAMC2,LAMA5
COLLAGEN METABOLIC PROCESS%GOBP%GO:0032963	collagen metabolic process	0.00522543091857117	0.00522543091857117	1	P3H2,P3H3,COL5A1,MRC2,PLOD1,MMP24,P3H1,MMP19,TNXB,PLOD3,MMP15,FURIN
CALCIUM REGULATION IN CARDIAC CELLS%WIKIPATHWAYS_20260910%WP536%HOMO SAPIENS	Calcium regulation in cardiac cells	0.00540152082007028	0.00540152082007028	1	GJB2,ADCY1,GNAI1,GNG4,GJB3,GJA3,SLC8A1,GRK5,RGS10,ADRA1B,PRKCZ,PRKD1,RGS14,PRKCE,ADCY3,GJC2,CAMK1,ANXA6,PLCB3,PRKAR1B
DEVELOPMENTAL LINEAGE OF PANCREATIC DUCTAL CELLS%REACTOME DATABASE ID RELEASE 97%9925563	Developmental Lineage of Pancreatic Ductal Cells	0.00556410457344712	0.00556410457344712	1	LAMB3,LAMB1,LAMA4,LAMC3,LAMC2,LAMA5
POSITIVE REGULATION OF PROTEIN LOCALIZATION TO SYNAPSE%GOBP%GO:1902474	positive regulation of protein localization to synapse	0.00589964152703056	0.00589964152703056	1	WNT5A,MAPT,DVL1,NLGN2
REGULATION OF IGF ACTIVITY BY IGFBP%REACTOME DATABASE ID RELEASE 97%381426	Regulation of IGF Activity by IGFBP	0.00590343636286879	0.00590343636286879	1	FBN1,SERPINA1,C3,MFGE8,MSLN,IGFBP6,TNC,TIMP1,LGALS1,LAMB1,FSTL3,FAM20C,CSF1,SDC2,GAS6,QSOX1,CDH2,GOLM1,RCN1,MELTF
STRIATED MUSCLE CONTRACTION%PATHWHIZ%PW000564	Striated Muscle Contraction	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ATENOLOL ACTION PATHWAY%SMPDB%SMP0000298	Atenolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ACEBUTOLOL ACTION PATHWAY%SMPDB%SMP0000296	Acebutolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
BISOPROLOL ACTION PATHWAY%SMPDB%SMP0000300	Bisoprolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
BETAXOLOL ACTION PATHWAY%SMPDB%SMP0000299	Betaxolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ALPRENOLOL ACTION PATHWAY%SMPDB%SMP0000297	Alprenolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
FELODIPINE ACTION PATHWAY%PATHWHIZ%PW000392	Felodipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ISRADIPINE ACTION PATHWAY%PATHWHIZ%PW000393	Isradipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
VERAPAMIL ACTION PATHWAY%SMPDB%SMP0000375	Verapamil Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
DILTIAZEM ACTION PATHWAY%SMPDB%SMP0000359	Diltiazem Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
IBUTILIDE ACTION PATHWAY%SMPDB%SMP0000332	Ibutilide Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
FLECAINIDE ACTION PATHWAY%SMPDB%SMP0000331	Flecainide Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NEBIVOLOL ACTION PATHWAY%SMPDB%SMP0000366	Nebivolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
TOCAINIDE ACTION PATHWAY%SMPDB%SMP0000330	Tocainide Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NITRENDIPINE ACTION PATHWAY%SMPDB%SMP0000382	Nitrendipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NISOLDIPINE ACTION PATHWAY%PATHWHIZ%PW000396	Nisoldipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NIMODIPINE ACTION PATHWAY%PATHWHIZ%PW000395	Nimodipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NIFEDIPINE ACTION PATHWAY%PATHWHIZ%PW000394	Nifedipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
PROCAINAMIDE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000377	Procainamide (Antiarrhythmic) Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
SOTALOL ACTION PATHWAY%SMPDB%SMP0000660	Sotalol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ARBUTAMINE ACTION PATHWAY%SMPDB%SMP0000664	Arbutamine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
BOPINDOLOL ACTION PATHWAY%SMPDB%SMP0000657	Bopindolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
CARTEOLOL ACTION PATHWAY%PATHWHIZ%PW000634	Carteolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
TIMOLOL ACTION PATHWAY%PATHWHIZ%PW000636	Timolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
DISOPYRAMIDE ACTION PATHWAY%SMPDB%SMP0000325	Disopyramide Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
PINDOLOL ACTION PATHWAY%PATHWHIZ%PW000374	Pindolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
FOSPHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000379	Fosphenytoin (Antiarrhythmic) Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
MEXILETINE ACTION PATHWAY%PATHWHIZ%PW000382	Mexiletine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
POSITIVE REGULATION OF VASCULATURE DEVELOPMENT%GOBP%GO:1904018	positive regulation of vasculature development	0.00600890085077649	0.00600890085077649	1	SERPINE1,F3,ITGA5,ANGPTL4,TGM2,ADAM12,HMGA2,FGF2,TWIST1,SPHK1,CLIC3,WNT5A,ITGAX,FLT1,TGFB1,ANXA3,PRKD1,EMC10,DLL1,MYDGF
HALLMARK_COAGULATION%MSIGDBHALLMARK%HALLMARK_COAGULATION%MSIGDBHALLMARK%HALLMARK_COAGULATION%MSIGDBHALLMARK%HALLMARK_COAGULATION	HALLMARK_COAGULATION%MSigdbHallmark%HALLMARK_COAGULATION	0.00600890085077649	0.00600890085077649	1	F3,FBN1,SERPINA1,THBD,KLF7,HTRA1,TIMP1,TFPI2,ITGB3,ANXA1,CPQ,BMP1,C1S,PLAT,MAFF,SH2B2,MMP15,FURIN
QUINIDINE ACTION PATHWAY%SMPDB%SMP0000323	Quinidine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
REGULATION OF COAGULATION%GOBP%GO:0050818	regulation of coagulation	0.00600890085077649	0.00600890085077649	1	CAV1,SERPINE1,F3,F2R,PROCR,SERPINE2,THBD,C1QTNF1,F2RL1,SH2B3,PLAUR,PLAU,PLAT
O-LINKED GLYCOSYLATION%REACTOME DATABASE ID RELEASE 97%5173105	O-linked glycosylation	0.00600890085077649	0.00600890085077649	1	ADAMTS7,ADAMTSL4,GALNT18,GALNT14,ADAMTS16,POMT1,THSD4,ADAMTS14,ADAMTSL3,GALNT2,ADAMTS17,LARGE2,ST6GALNAC4,B3GNT9,ST3GAL2,THSD1,B3GNT4,MGAT5B,GCNT1,ADAMTS15
BUPRANOLOL ACTION PATHWAY%SMPDB%SMP0000670	Bupranolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
REGULATION OF ENDOCYTOSIS%GOBP%GO:0030100	regulation of endocytosis	0.00600890085077649	0.00600890085077649	1	CAV1,AXL,SERPINE1,CYBA,TGM2,LRP1,C3,ANKRD13A,RSPO1,F2RL1,ANXA2,SPHK1,ITGB3,SNX33,GAS6,SIRPB1,APLN,DGKD,CD151,ANKRD13B,HIP1,PRKD1,NECAB2,PRTN3,SCARB1,AZU1,DLL1,SIRPA,WDR54,ABCA2,IQSEC1
AXON GUIDANCE%WIKIPATHWAYS_20260910%WP5289%HOMO SAPIENS	Axon guidance	0.00600890085077649	0.00600890085077649	1	DPYSL5,L1CAM,SEMA7A,GNAI1,EPHA2,SHH,NTNG2,SLIT3,BOC,SLIT2,PRKCZ,SLIT1,ROBO3
REGULATION OF WOUND HEALING%GOBP%GO:0061041	regulation of wound healing	0.00600890085077649	0.00600890085077649	1	CAV1,SERPINE1,F3,F2R,SERPINE2,THBD,FGF2,C1QTNF1,AJAP1,F2RL1,PHLDB2,MYLK,SH2B3,PLAUR,ANXA1,ACTG1,PLAU,PLAT,PRKCE
EPINEPHRINE ACTION PATHWAY%PATHWHIZ%PW000638	Epinephrine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
DOBUTAMINE ACTION PATHWAY%PATHWHIZ%PW000639	Dobutamine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ISOPRENALINE ACTION PATHWAY%SMPDB%SMP0000663	Isoprenaline Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
PENBUTOLOL ACTION PATHWAY%SMPDB%SMP0000305	Penbutolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
NADOLOL ACTION PATHWAY%PATHWHIZ%PW000371	Nadolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
OXPRENOLOL ACTION PATHWAY%PATHWHIZ%PW000372	Oxprenolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
ESMOLOL ACTION PATHWAY%SMPDB%SMP0000301	Esmolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
METOPROLOL ACTION PATHWAY%PATHWHIZ%PW000370	Metoprolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
PROPRANOLOL ACTION PATHWAY%SMPDB%SMP0000307	Propranolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
PRACTOLOL ACTION PATHWAY%PATHWHIZ%PW000646	Practolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
METIPRANOLOL ACTION PATHWAY%PATHWHIZ%PW000644	Metipranolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
LEVOBUNOLOL ACTION PATHWAY%SMPDB%SMP0000666	Levobunolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
BEVANTOLOL ACTION PATHWAY%PATHWHIZ%PW000645	Bevantolol Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
AMLODIPINE ACTION PATHWAY%PATHWHIZ%PW000391	Amlodipine Action Pathway	0.00600890085077649	0.00600890085077649	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
DEVELOPMENTAL LINEAGE OF PANCREATIC ENDOCRINE MID PROGENITOR CELLS%REACTOME DATABASE ID RELEASE 97%9981148	Developmental Lineage of Pancreatic Endocrine Mid Progenitor Cells	0.0060948287567645	0.0060948287567645	1	LAMB3,LAMB1,LAMA4,LAMC3,LAMC2,LAMA5
DIRECT P53 EFFECTORS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%DIRECT P53 EFFECTORS	Direct p53 effectors	0.00623796931482482	0.00623796931482482	1	CAV1,SERPINE1,NDRG1,LIF,EPHA2,EGFR,DUSP1,COL18A1,S100A2,DUSP5,MET,PRDM1,TNFRSF10C,PCBP4,PML,DDIT4,HIC1,PLK3,BID,SNAI2,GADD45A
REGULATION OF MONOATOMIC CATION TRANSMEMBRANE TRANSPORT%GOBP%GO:1904062	regulation of monoatomic cation transmembrane transport	0.00648178337838461	0.00648178337838461	1	CAV1,BIN1,F2R,FXYD5,TESC,FHL1,SLC8A1,KCNAB2,STAC2,KCNH2,KCNG1,UBASH3B,CBARP,SNTA1,SCN1B,KCNIP3,JPH2,PML,SCN5A,KCNS3,SPHK2,WNK2,PRKCE,CRACR2A,ADAM23,P2RX5,JPH3,TMEM38A
TYPE I COLLAGEN SYNTHESIS IN THE CONTEXT OF OSTEOGENESIS IMPERFECTA%WIKIPATHWAYS_20260910%WP4786%HOMO SAPIENS	Type I collagen synthesis in the context of osteogenesis imperfecta	0.00661074157516783	0.00661074157516783	1	P3H2,PLOD1,P3H1,CRTAP,P4HA2,COLGALT1,BMP1,PPIB
CARVEDILOL ACTION PATHWAY%SMPDB%SMP0000367	Carvedilol Action Pathway	0.00705312495783487	0.00705312495783487	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
AMIODARONE ACTION PATHWAY%PATHWHIZ%PW000642	Amiodarone Action Pathway	0.00705312495783487	0.00705312495783487	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H,PRKAR1B
LABETALOL ACTION PATHWAY%PATHWHIZ%PW000389	Labetalol Action Pathway	0.00705312495783487	0.00705312495783487	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
REGULATION OF CELL-MATRIX ADHESION%GOBP%GO:0001952	regulation of cell-matrix adhesion	0.00709923211790394	0.00709923211790394	1	SERPINE1,DLC1,AJAP1,PHLDB2,CSF1,ACTG1,MINK1,CORO1C,PLAU,NF2,PPM1F,CIB1,S100A10,CDKN2A,PLEKHA2,DAPK3,MACF1,IQSEC1
NEGATIVE REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS%GOBP%GO:0090288	negative regulation of cellular response to growth factor stimulus	0.00709923211790394	0.00709923211790394	1	FBN1,CRIM1,FGF2,NOG,FSTL3,NBL1,GPC1,SPRY4,CREB3L1,APLN,SLIT2,ERFE,PPARG,SMURF2,HGS
HIPPO SIGNALING REGULATION%WIKIPATHWAYS_20260910%WP4540%HOMO SAPIENS	Hippo signaling regulation	0.0080806931359389	0.0080806931359389	1	EPHA2,EGFR,IGF1R,PRKAG2,FLT1,CDH2,CDH15,TEAD4,NF2,PRKCZ,PRKCE,NGFR,PLCB3,PRKAR1B
REGULATION OF BLOOD COAGULATION%GOBP%GO:0030193	regulation of blood coagulation	0.00810927994199791	0.00810927994199791	1	CAV1,SERPINE1,F3,F2R,SERPINE2,THBD,C1QTNF1,F2RL1,SH2B3,PLAUR,PLAU,PLAT
NEGATIVE REGULATION OF CELL-SUBSTRATE ADHESION%GOBP%GO:0010812	negative regulation of cell-substrate adhesion	0.00810927994199791	0.00810927994199791	1	SERPINE1,CORO2B,FBLN1,DLC1,SPOCK1,AJAP1,PHLDB2,CORO1C,SPRY4,NF2,CDKN2A,MELTF
COAGULATION PATHWAY%REACTOME DATABASE ID RELEASE 97%9769740	Coagulation pathway	0.00810927994199791	0.00810927994199791	1	SERPINE1,F3,F2R,PROCR,SERPINE2,THBD,SDC2,ITGB3,GPC1,AGRN,HSPG2,PRTN3
LIDOCAINE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000381	Lidocaine (Antiarrhythmic) Action Pathway	0.00824396992049362	0.00824396992049362	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,TPM2,ABCC8,CACNA1H
MESODERMAL CELL DIFFERENTIATION%GOBP%GO:0048333	mesodermal cell differentiation	0.00884964896942685	0.00884964896942685	1	HMGA2,ITGB4,SIX2,ITGA3,ITGB3,EYA2
REGULATION OF VASCULATURE DEVELOPMENT%GOBP%GO:1901342	regulation of vasculature development	0.00943763183013655	0.00943763183013655	1	SERPINE1,F3,ADGRB1,ITGA5,ANGPTL4,TGM2,ADAM12,HMGA2,EPHA2,FGF2,TWIST1,SPHK1,CLIC3,WNT5A,ITGAX,FLT1,TGFB1,HSPG2,ANXA3,VASH1,CREB3L1,ISM1,PML,PRKD1,NPR1,EMC10,DLL1,PPARG,MYDGF,HGS
REGULATION OF HEMOSTASIS%GOBP%GO:1900046	regulation of hemostasis	0.00943763183013655	0.00943763183013655	1	CAV1,SERPINE1,F3,F2R,SERPINE2,THBD,C1QTNF1,F2RL1,SH2B3,PLAUR,PLAU,PLAT
RESPONSE TO GROWTH FACTOR%GOBP%GO:0070848	response to growth factor	0.00954327967401429	0.00954327967401429	1	ADAMTS7,EPHA2,CD44,EGFR,FGF2,ID1,SPHK1,ZYX,SMAD3,WNT5A,MYC,GAS1,PSG9,PDE2A,ANXA1,TGFBR2,SMAD4,BMP7,FLT1,TGFB1,LTBP3,WNT10A,FAM83G,CIB1,PRKD1,FNDC4,MAPT,DDIT4,PGF,RGMB,PPARG,ZFP36L2,MYO1C,HTRA2,MAP2K5,FURIN,SNAI2
MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260910%WP289%HOMO SAPIENS	Myometrial relaxation and contraction pathways	0.00954327967401429	0.00954327967401429	1	RAMP1,ADCY1,GNG4,ADM,IGFBP6,SLC8A1,ETS2,GRK5,RGS10,CNN2,ACTG1,PRKCZ,PRKD1,MAFF,RGS14,PRKCE,ADCY3,PLCB3,PRKAR1B
NEGATIVE REGULATION OF ENDOTHELIAL CELL MIGRATION%GOBP%GO:0010596	negative regulation of endothelial cell migration	0.00954327967401429	0.00954327967401429	1	ADGRB1,FGF2,STC1,TGFB1,VASH1,SLIT2,TBXA2R,CARD10,PPARG,MAP2K5,GADD45A
POSITIVE REGULATION OF ANGIOGENESIS%GOBP%GO:0045766	positive regulation of angiogenesis	0.00954327967401429	0.00954327967401429	1	SERPINE1,F3,ITGA5,ANGPTL4,TGM2,ADAM12,HMGA2,FGF2,TWIST1,SPHK1,CLIC3,WNT5A,ITGAX,FLT1,ANXA3,PRKD1,EMC10,DLL1,MYDGF
REGULATION OF CLOTTING CASCADE%REACTOME DATABASE ID RELEASE 97%9769739	Regulation of clotting cascade	0.00954327967401429	0.00954327967401429	1	SERPINE1,F3,F2R,PROCR,SERPINE2,THBD,SDC2,GPC1,AGRN,HSPG2,PRTN3
LOSS OF FUNCTION OF SMAD2 3 IN CANCER%REACTOME DATABASE ID RELEASE 97%3304349	Loss of Function of SMAD2 3 in Cancer	0.00974893365294425	0.00974893365294425	1	SMAD3,TGFBR2,SMAD4,TGFB1
REGULATION OF PLASMA MEMBRANE REPAIR%GOBP%GO:1905684	regulation of plasma membrane repair	0.00974893365294425	0.00974893365294425	1	ANXA2,MYH9,S100A10,RAB3A
ENDOTHELIAL CELL MORPHOGENESIS%GOBP%GO:0001886	endothelial cell morphogenesis	0.00974893365294425	0.00974893365294425	1	STC1,COL18A1,MET,AMOTL2
INTEGRIN-MEDIATED SIGNALING PATHWAY%GOBP%GO:0007229	integrin-mediated signaling pathway	0.00976369185704714	0.00976369185704714	1	ITGA5,SEMA7A,ITGB4,ZYX,ADAM11,ITGA3,ITGAX,ITGB3,LAMA5,MYH9,ISG15,ITGA6,DOCK1,PRKD1,ITGB2
REGULATION OF METAL ION TRANSPORT%GOBP%GO:0010959	regulation of metal ion transport	0.00976369185704714	0.00976369185704714	1	CAV1,BIN1,F2R,FXYD5,WNK4,TESC,FHL1,STC1,SLC8A1,MYLK,KCNAB2,KCNH2,KCNG1,HOMER3,UBASH3B,CBARP,SNTA1,SCN1B,KCNIP3,JPH2,PML,SCN5A,KCNS3,WNK2,PRKCE,CRACR2A,ADAM23,P2RX5,PER1,NKAIN1,JPH3,TMEM38A
MET PROMOTES CELL MOTILITY%REACTOME DATABASE ID RELEASE 97%8875878	MET promotes cell motility	0.0102577548168329	0.0102577548168329	1	LAMB3,LAMB1,ITGA3,LAMA4,LAMC3,LAMC2,LAMA5,MET
REGULATION OF ENDOTHELIAL CELL MIGRATION%GOBP%GO:0010594	regulation of endothelial cell migration	0.0104480943184347	0.0104480943184347	1	ADGRB1,EPHA2,FGF2,STC1,WNT5A,ITGB3,ANXA1,MET,TGFB1,ANXA3,VASH1,SLIT2,CIB1,TBXA2R,PRKD1,SCARB1,EMC10,CARD10,PPARG,MAP2K5,JCAD,GADD45A
REGULATION OF MONOATOMIC ION TRANSMEMBRANE TRANSPORT%GOBP%GO:0034765	regulation of monoatomic ion transmembrane transport	0.0104731177385743	0.0104731177385743	1	CAV1,BIN1,F2R,FXYD5,TESC,FHL1,SLC8A1,KCNAB2,STAC2,KCNH2,KCNG1,UBASH3B,CBARP,SNTA1,SCN1B,KCNIP3,JPH2,PML,SCN5A,KCNS3,SPHK2,WNK2,PRKCE,CRACR2A,ADAM23,P2RX5,JPH3,TMEM38A
DISEASES OF GLYCOSYLATION%REACTOME DATABASE ID RELEASE 97%3781865	Diseases of glycosylation	0.0107438410688643	0.0107438410688643	1	ADAMTS7,ADAMTSL4,BGN,CHST3,EXT1,ADAMTS16,POMT1,THSD4,ADAMTS14,ADAMTSL3,SDC2,GPC1,CHSY1,AGRN,HSPG2,ADAMTS17,GALK1,THSD1,CSPG5,CTSA,ADAMTS15
EPITHELIAL CELL DEVELOPMENT%GOBP%GO:0002064	epithelial cell development	0.0107686425263018	0.0107686425263018	1	SOX8,EPHA2,PODXL,F2RL1,STC1,ROBO4,COL18A1,PDE2A,MET,CDH2,AMOTL2,MYO1E,DLL1,STX2,MYADM
SYNAPSE ORGANIZATION%GOBP%GO:0050808	synapse organization	0.0107686425263018	0.0107686425263018	1	F2R,L1CAM,DNER,ELFN1,C3,NTNG1,TENM2,TENM3,IGF1R,PLXNA2,ITGA3,SNCG,C1QL1,WNT5A,LRP4,NTNG2,RAC3,CDH2,AGRN,SHANK3,PPFIA4,PALM,SDK2,LRFN4,DOCK10,MAPT,DVL1,NLGN2,PCDHGC5,BSN
REGULATION OF RESPONSE TO WOUNDING%GOBP%GO:1903034	regulation of response to wounding	0.010869867253349	0.010869867253349	1	CAV1,SERPINE1,F3,F2R,SERPINE2,THBD,FGF2,C1QTNF1,AJAP1,F2RL1,PHLDB2,MYLK,SH2B3,PLAUR,ANXA1,ACTG1,PLAU,PLAT,PRKCE,GIT1
BETA OXIDATION OF PALMITOYL-COA TO MYRISTOYL-COA%REACTOME%R-HSA-77305.3	Beta oxidation of palmitoyl-CoA to myristoyl-CoA	0.0110818723816624	0.0110818723816624	1	HADHB,ACADVL,HADHA
REGULATION OF ACTIN CYTOSKELETON ORGANIZATION%GOBP%GO:0032956	regulation of actin cytoskeleton organization	0.0113077613765434	0.0113077613765434	1	CORO2B,BIN1,CSF3,CDC42EP3,DLC1,LRP1,F2RL1,FHOD3,PHLDB2,FSCN1,NGEF,COTL1,TRIP10,CARMIL2,SMAD4,ACTG1,RAC3,SHANK3,ARAP3,CDC42EP1,RHOF,NF2,SLIT2,SSH1,PPM1F,S100A10,CCDC88A,LIMK1,PRKCE,DAPK3,FLII,BRK1,RAB40B,MYADM
HEMOPOIESIS%GOBP%GO:0030097	hemopoiesis	0.0121979800070669	0.0121979800070669	1	AXL,IL7R,MXRA7,CSF3,LIF,EPHA2,TCF7,F2RL1,IL11,SHH,ANXA2,SH2B3,FSTL3,EPAS1,WNT5A,CSF1,ANXA1,TGFBR2,GAS6,MEIS3,WNT10B,TGFB1,CBFA2T3,MYH9,RELB,FTL,KLF6,SELENOW,SOCS3,IGSF23,CIB1,NFIL3,CLCF1,DOCK10,CEBPB,ACTN1,PRTN3,PSMA7,P2RX5,JAG2,DLL1,PPARG,ZFP36L2,JAK3,THOC5,DYRK3
CELL-CELL ADHESION%GOBP%GO:0098609	cell-cell adhesion	0.0121979800070669	0.0121979800070669	1	TGFBI,ITGA5,L1CAM,CD44,ITGB4,EGFR,NT5E,NTNG1,POPDC3,TENM2,TENM3,FBLIM1,LGALS1,LAMB1,ITGA3,COL13A1,ROBO4,KIFC3,ITGAX,MMP24,CLDN23,ITGB3,TGFBR2,PVR,ACTG1,UBASH3B,NTNG2,BMP7,NFASC,CDH2,CDH15,BOC,SDK2,LRFN4,IGSF23,TNIP1,MYPN,ITGA6,FGFRL1,NLGN2,ROBO3,PODXL2,ITGB2,CADM1,SELPLG,GCNT1
REGULATION OF ANGIOGENESIS%GOBP%GO:0045765	regulation of angiogenesis	0.012302441685569	0.012302441685569	1	SERPINE1,F3,ADGRB1,ITGA5,ANGPTL4,TGM2,ADAM12,HMGA2,EPHA2,FGF2,TWIST1,SPHK1,CLIC3,WNT5A,ITGAX,FLT1,HSPG2,ANXA3,VASH1,CREB3L1,ISM1,PML,PRKD1,NPR1,EMC10,DLL1,PPARG,MYDGF,HGS
NEGATIVE CHEMOTAXIS%GOBP%GO:0050919	negative chemotaxis	0.0124673778446279	0.0124673778446279	1	SEMA7A,SEMA4B,WNT5A,NTN1,ITGB3,SLIT3,SLIT2,SLIT1
HALLMARK_INFLAMMATORY_RESPONSE%MSIGDBHALLMARK%HALLMARK_INFLAMMATORY_RESPONSE%MSIGDBHALLMARK%HALLMARK_INFLAMMATORY_RESPONSE%MSIGDBHALLMARK%HALLMARK_INFLAMMATORY_RESPONSE	HALLMARK_INFLAMMATORY_RESPONSE%MSigdbHallmark%HALLMARK_INFLAMMATORY_RESPONSE	0.0124673778446279	0.0124673778446279	1	AXL,IL7R,F3,CSF3,LIF,PTGIR,ADM,ABCA1,TIMP1,OSMR,SPHK1,IFITM1,PLAUR,ADORA2B,MYC,CSF1,ITGB3,EMP3,IRAK2,SCN1B,KLF6,HRH1,TPBG,PCDH7
MOLECULES ASSOCIATED WITH ELASTIC FIBRES%REACTOME DATABASE ID RELEASE 97%2129379	Molecules associated with elastic fibres	0.0124673778446279	0.0124673778446279	1	FBLN1,ITGB3,BMP7,TGFB1,LTBP3,FBLN2,MFAP4,MFAP2
COLLAGEN CHAIN TRIMERIZATION%REACTOME DATABASE ID RELEASE 97%8948216	Collagen chain trimerization	0.012488012127827	0.012488012127827	1	COL6A1,COL6A2,COL5A1,COL12A1,COL27A1,COL13A1,COL18A1,COL6A3,COL9A3,COL23A1
HALLMARK_TGF_BETA_SIGNALING%MSIGDBHALLMARK%HALLMARK_TGF_BETA_SIGNALING%MSIGDBHALLMARK%HALLMARK_TGF_BETA_SIGNALING%MSIGDBHALLMARK%HALLMARK_TGF_BETA_SIGNALING	HALLMARK_TGF_BETA_SIGNALING%MSigdbHallmark%HALLMARK_TGF_BETA_SIGNALING	0.012488012127827	0.012488012127827	1	NOG,ID1,ID3,TGFB1,SPTBN1,CDKN1C,KLF10,PPP1R15A,SMURF2,FURIN
FOCAL ADHESION%WIKIPATHWAYS_20260910%WP306%HOMO SAPIENS	Focal adhesion	0.0126959540674022	0.0126959540674022	1	LAMB3,CAV2,ITGB4,EGFR,TNC,LAMB1,MYLK,IGF1R,ZYX,PARVB,LAMA4,ITGB3,FLNB,LAMC2,LAMA5,ACTG1,SHC2,FLT1,RAC3,ITGA6,ACTN1,DOCK1
POSITIVE REGULATION OF EXTRACELLULAR MATRIX DISASSEMBLY%GOBP%GO:0090091	positive regulation of extracellular matrix disassembly	0.0133086162441877	0.0133086162441877	1	FSCN1,PLAUR,CARMIL2,PLAU,MELTF
REGULATION OF MITF-M-DEPENDENT GENES INVOLVED IN EXTRACELLULAR MATRIX, FOCAL ADHESION AND EPITHELIAL-TO-MESENCHYMAL TRANSITION%REACTOME DATABASE ID RELEASE 97%9926550	Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	0.0133086162441877	0.0133086162441877	1	SERPINE1,GXYLT2,PXDN,CDH2,ZEB1
POSITIVE REGULATION OF CELL DEVELOPMENT%GOBP%GO:0010720	positive regulation of cell development	0.013450326643585	0.013450326643585	1	AXL,BIN1,L1CAM,SEMA7A,TESC,SERPINE2,TGM2,SOX8,LIF,SHH,SMARCD3,DBN1,CSF1,NTN1,ANXA1,TGFBR2,GAS6,CORO1C,TGFB1,CDH2,SHANK3,RASSF10,TM4SF19,SLIT2,PRKCZ,NUMBL,CLCF1,IL4R,LIMK1,MAPT,RGS14,DDRGK1,MACF1
POSITIVE REGULATION OF LIPID LOCALIZATION%GOBP%GO:1905954	positive regulation of lipid localization	0.013450326643585	0.013450326643585	1	CAV1,PLIN2,LRP1,C3,C1QTNF1,ANXA2,GPIHBP1,ZDHHC8,GAL,PLIN3,PLTP,NMB,SCARB1,PPARG
EGFR1%IOB%EGFR1	EGFR1	0.0138561375331948	0.0138561375331948	1	AXL,RIN1,TRIP6,CRIM1,CAV2,EPHA2,ITGB4,EGFR,CAVIN1,ARHGEF4,ANXA2,PHLDB2,MAP3K14,MYC,EEF1A2,ANXA1,FLNB,SH3GL3,CSTB,MINK1,SNX33,UBASH3B,PLEC,MYH9,CDH2,SPRY4,SHB,SOCS3,PRKCZ,S100A10,CEBPB,ACTN1,DOCK1,PRKD1,PPP1R14B,SIRPA,DYRK3,MAP2K5,PLEKHN1,HGS
MIR TARGETED GENES IN LEUKOCYTES%WIKIPATHWAYS_20260910%WP2003%HOMO SAPIENS	miR targeted genes in leukocytes	0.0138561375331948	0.0138561375331948	1	MRC2,SERPINE2,ANXA2,SH3BGRL3,TNFAIP2,CORO1C,TMED3,GYS1,UNC93B1,RTN4,CEBPB,PHC2,PPIB,ATP6V1F,FMNL2,TMEM43,HMGA1
MIR TARGETED GENES IN SQUAMOUS CELL%WIKIPATHWAYS_20260910%WP2006%HOMO SAPIENS	miR targeted genes in squamous cell	0.0138561375331948	0.0138561375331948	1	AXL,MRC2,FGF2,PDLIM7,ANXA2,PXDN,SH3BGRL3,TGFBR2,P4HA2,GYS1,NF2,RTN4,ATP6V1F,FMNL2,TMEM43,HMGA1,SH3BP4
VALIDATED TRANSCRIPTIONAL TARGETS OF AP1 FAMILY MEMBERS FRA1 AND FRA2%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%VALIDATED TRANSCRIPTIONAL TARGETS OF AP1 FAMILY MEMBERS FRA1 AND FRA2	Validated transcriptional targets of AP1 family members Fra1 and Fra2	0.0139718404961927	0.0139718404961927	1	FOSL1,NFATC2,LIF,THBD,ITGB4,PLAUR,PLAU,CDKN2A,FOSL2
ENDODERM FORMATION%GOBP%GO:0001706	endoderm formation	0.0143954317996006	0.0143954317996006	1	COL6A1,ITGA5,LAMB3,HMGA2,COL12A1,DUSP1,LAMB1,DUSP5,ITGB2,MMP15
TGF-BETA RECEPTOR SIGNALING ACTIVATES SMADS%REACTOME%R-HSA-2173789.6	TGF-beta receptor signaling activates SMADs	0.0143954317996006	0.0143954317996006	1	PMEPA1,SMAD3,ITGB3,TGFBR2,SMAD4,TGFB1,LTBP3,PPP1R15A,SMURF2,FURIN
RESPIRATORY SYNCYTIAL VIRUS (RSV) ATTACHMENT AND ENTRY%REACTOME%R-HSA-9820960.2	Respiratory syncytial virus (RSV) attachment and entry	0.0145248051137175	0.0145248051137175	1	EGFR,IGF1R,SDC2,GPC1,AGRN,HSPG2,FURIN
CELL-SUBSTRATE JUNCTION ASSEMBLY%GOBP%GO:0007044	cell-substrate junction assembly	0.0149503083133162	0.0149503083133162	1	CORO2B,TRIP6,DLC1,ITGB4,PLEC,ITGA6,ACTN1,THSD1
CIRCULATORY SYSTEM PROCESS%GOBP%GO:0003013	circulatory system process	0.0149503083133162	0.0149503083133162	1	CAV1,KCNK3,F2R,LRP1,ADM,F2RL1,HTR7,KCNMA1,SLC29A4,SLC8A1,RASL10B,MYLK,KCNH2,FABP5,ADORA2B,SLC6A6,HCN4,PDE2A,AGTRAP,SNTA1,TGFB1,SCN1B,APLN,SLIT2,TBXA2R,SCN5A,SCN8A,SCARB1,ECE1,SLC4A3,NPR1,AZU1,DLL1,SCNN1D,PPARG,SGK1,ABCA2,SLC2A1,SLCO3A1,PLCB3
EMBRYO DEVELOPMENT%GOBP%GO:0009790	embryo development	0.0161025262301324	0.0161025262301324	1	COL6A1,ITGA5,FBN1,SOX8,LAMB3,HMGA2,COL12A1,DLC1,ALDH1A3,ITGB4,FGF2,PKDCC,HOXB9,DUSP1,SIX2,SHH,NOG,TWIST1,LAMB1,SH2B3,ITGA3,WNT5A,DUSP5,ITGB3,TGFBR2,MEIS3,BMP7,FLT1,TGFB1,MFAP2,TEAD4,DVL1,ECE1,BASP1,MTHFD1L,PBX4,DLL1,AHDC1,NR4A3,ITGB2,EYA2,THOC5,PRICKLE1,ZP3,CYP26B1,MMP15,NES
LUNG FIBROSIS%WIKIPATHWAYS_20260910%WP3624%HOMO SAPIENS	Lung fibrosis	0.0161037872299079	0.0161037872299079	1	CSF3,SERPINA1,CTGF,FGF2,TIMP1,MT2A,BMP7,ATP11A,TGFB1,CEBPB,DPP9
DEFECTIVE B3GALTL CAUSES PPS%REACTOME DATABASE ID RELEASE 97%5083635	Defective B3GALTL causes PpS	0.0166845610198121	0.0166845610198121	1	ADAMTS7,ADAMTSL4,ADAMTS16,THSD4,ADAMTS14,ADAMTSL3,ADAMTS17,THSD1,ADAMTS15
NEGATIVE REGULATION OF CELL POPULATION PROLIFERATION%GOBP%GO:0008285	negative regulation of cell population proliferation	0.0168167693442842	0.0168167693442842	1	CAV1,P3H2,P3H3,ADGRB1,F2R,FBLN1,TESC,CAV2,BTG3,DLC1,PTGIR,CGREF1,IGFBP6,NOG,SH2B3,SMAD3,COL18A1,IFITM1,WNT5A,MYC,P3H1,CNTFR,BMP7,FLT1,TGFB1,CBFA2T3,CDKN1C,VASH1,APLN,KLF10,ADGRG1,TES,NF2,CIB1,PML,SPEG,CDKN2A,CEBPB,WNK2,ADARB1,DLL1,NGFR,HMGA1,PPARG,MN1,SNAI2,IFI35,HGS,SH3BP4,LMNA
POSITIVE REGULATION OF CELL PROJECTION ORGANIZATION%GOBP%GO:0031346	positive regulation of cell projection organization	0.0173672741152278	0.0173672741152278	1	L1CAM,SEMA7A,CDC42EP3,TENM2,F2RL1,TENM3,FSCN1,WNT5A,P3H1,DBN1,NTN1,CARMIL2,CORO1C,BMP7,CDH2,SCN1B,PALM,CDC42EP1,SLIT2,ITGA6,CCDC88A,PRKD1,LIMK1,MAPT,KCTD17,DVL1,CAMK1,BRK1,MACF1,EPS8L2
REGULATION OF PROTEOLYSIS%GOBP%GO:0030162	regulation of proteolysis	0.0175525406216846	0.0175525406216846	1	SERPINE1,TIMP2,CCBE1,NKD2,SERPINE2,SHH,ANXA2,TIMP1,PLAUR,GAS1,CSTB,SNX33,MYH9,PLAU,PLAT,S100A10,MELTF,TIMP4,FURIN
NEGATIVE REGULATION OF PLASMINOGEN ACTIVATION%GOBP%GO:0010757	negative regulation of plasminogen activation	0.0176742211773167	0.0176742211773167	1	SERPINE1,SERPINE2,PLAU,PLAT
SIGNALING BY TGF-BETA RECEPTOR COMPLEX IN CANCER%REACTOME DATABASE ID RELEASE 97%3304351	Signaling by TGF-beta Receptor Complex in Cancer	0.0176742211773167	0.0176742211773167	1	SMAD3,TGFBR2,SMAD4,TGFB1
PHAGOCYTOSIS%GOBP%GO:0006909	phagocytosis	0.0177846686708846	0.0177846686708846	1	AXL,ADGRB1,SRPX,TGM2,LRP1,ITGAX,ITGB3,ANXA1,GAS6,CORO1C,MYH9,ANXA3,JMJD6,DOCK1,LIMK1,SCARB1,PRKCE,ITGB2
POSITIVE REGULATION OF DEVELOPMENTAL GROWTH%GOBP%GO:0048639	positive regulation of developmental growth	0.0181499235512281	0.0181499235512281	1	L1CAM,SEMA7A,FGF2,RNF157,NTN1,CDH2,AGRN,LIMK1,MAPT,PPIB,BASP1,DLL1,MACF1,ZP3
CELL-SUBSTRATE JUNCTION ORGANIZATION%GOBP%GO:0150115	cell-substrate junction organization	0.0181499235512281	0.0181499235512281	1	CORO2B,TRIP6,DLC1,ITGB4,PLEC,ITGA6,ACTN1,THSD1
POSITIVE REGULATION OF REACTIVE OXYGEN SPECIES METABOLIC PROCESS%GOBP%GO:2000379	positive regulation of reactive oxygen species metabolic process	0.0181499235512281	0.0181499235512281	1	ADGRB1,CYBA,F2RL1,PID1,TGFBR2,TGFB1,MAPT,PRKCE,ITGB2,SIRPA,GADD45A
POSITIVE REGULATION OF AXON EXTENSION%GOBP%GO:0045773	positive regulation of axon extension	0.0181499235512281	0.0181499235512281	1	L1CAM,SEMA7A,NTN1,CDH2,LIMK1,MAPT,MACF1
SIGNALING BY MET%REACTOME%R-HSA-6806834.4	Signaling by MET	0.0187976838586267	0.0187976838586267	1	LAMB3,LAMB1,ITGA3,LAMA4,LAMC3,SH3GL3,LAMC2,LAMA5,MET,SH3KBP1,SH3GL1,HGS
HALLMARK_ESTROGEN_RESPONSE_EARLY%MSIGDBHALLMARK%HALLMARK_ESTROGEN_RESPONSE_EARLY%MSIGDBHALLMARK%HALLMARK_ESTROGEN_RESPONSE_EARLY%MSIGDBHALLMARK%HALLMARK_ESTROGEN_RESPONSE_EARLY	HALLMARK_ESTROGEN_RESPONSE_EARLY%MSigdbHallmark%HALLMARK_ESTROGEN_RESPONSE_EARLY	0.0190996352279478	0.0190996352279478	1	FHL2,CALB2,ZNF185,ADCY1,ALDH3B1,CD44,IGF1R,CLIC3,NBL1,MYC,THSD4,FLNB,PTGES,CBFA2T3,KAZN,KLF10,MYBBP1A,RAPGEFL1,OLFML3,SCARB1,TPBG,DHRS3,CYP26B1
NEGATIVE REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY%GOBP%GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	0.0191376862259458	0.0191376862259458	1	FGF2,GPC1,SPRY4,CREB3L1,APLN
REGULATION OF SYSTEM PROCESS%GOBP%GO:0044057	regulation of system process	0.0191550143760612	0.0191550143760612	1	CAV1,PDE9A,BIN1,F2R,GNAI1,ADM,C1QTNF1,F2RL1,TSHZ3,STC1,SLC8A1,SPHK1,MYLK,KCNH2,ITGAX,MAPK8IP2,TNNT1,HCN4,SMAD4,CDK18,GAS6,ATP1A3,SNTA1,SCN1B,SHANK3,APLN,GAL,ADRA1B,JPH2,PRKCZ,TBXA2R,SCN5A,FBXO32,ECE1,NLGN2,SLC4A3,DAPK3,NPR1,NR4A3,PPARG,JPH3,CACNA1H,LMNA
O-GLYCOSYLATION OF TSR DOMAIN-CONTAINING PROTEINS%REACTOME DATABASE ID RELEASE 97%5173214	O-glycosylation of TSR domain-containing proteins	0.0192017777414269	0.0192017777414269	1	ADAMTS7,ADAMTSL4,ADAMTS16,THSD4,ADAMTS14,ADAMTSL3,ADAMTS17,THSD1,ADAMTS15
PROTEIN O-LINKED GLYCOSYLATION%GOBP%GO:0006493	protein O-linked glycosylation	0.0201137630165512	0.0201137630165512	1	GXYLT2,GALNT18,HS3ST3A1,CHST3,GALNT14,EXT1,TMTC1,POMT1,GALNT2,CHSY1,COLGALT1,LARGE2,ST6GALNAC4,DSE,PLOD3,ST3GAL2,CHPF2,MGAT5B,GCNT1
BLOOD CIRCULATION%GOBP%GO:0008015	blood circulation	0.0204842061942242	0.0204842061942242	1	CAV1,KCNK3,F2R,ADM,F2RL1,HTR7,KCNMA1,SLC8A1,RASL10B,MYLK,KCNH2,ADORA2B,HCN4,PDE2A,AGTRAP,SNTA1,TGFB1,SCN1B,APLN,SLIT2,TBXA2R,SCN5A,SCN8A,SCARB1,ECE1,NPR1,AZU1,DLL1,SCNN1D,PPARG,SGK1,PLCB3
AXON GUIDANCE MEDIATED BY SLIT ROBO%PANTHER PATHWAY%P00008	Axon guidance mediated by Slit Robo	0.0204842061942242	0.0204842061942242	1	NTNG1,NTN1,NTNG2,SLIT3,SLIT2,SLIT1
POSITIVE REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002720	positive regulation of cytokine production involved in immune response	0.0204946779243731	0.0204946779243731	1	SEMA7A,F2RL1,HLA-F,WNT5A,SECTM1,HLA-A,PRKCZ,RAET1G,SPHK2,TICAM1,NR4A3
POSITIVE REGULATION OF PRODUCTION OF MOLECULAR MEDIATOR OF IMMUNE RESPONSE%GOBP%GO:0002702	positive regulation of production of molecular mediator of immune response	0.0206178663330974	0.0206178663330974	1	SEMA7A,F2RL1,HLA-F,WNT5A,SECTM1,GALNT2,HLA-A,TGFB1,PRKCZ,RAET1G,CLCF1,SPHK2,MAD2L2,TICAM1,NR4A3
MESENCHYMAL CELL DIFFERENTIATION%GOBP%GO:0048762	mesenchymal cell differentiation	0.0208380057299236	0.0208380057299236	1	SOX8,LOXL2,HMGA2,SIX2,SHH,NOG,WNT5A,AKNA,TGFBR2,SMAD4,S100A4,CORO1C,BMP7,TGFB1,CDH2,GFAP,SNAI2
NEGATIVE REGULATION OF MAPK CASCADE%GOBP%GO:0043409	negative regulation of MAPK cascade	0.0215131799704323	0.0215131799704323	1	CAV1,FBLN1,F2RL1,DUSP1,IGF1R,SH2B3,MYC,DUSP5,SMAD4,DUSP9,SPRY4,SPRED3,TNIP1,DUSP7,RGS14,WNK2,PER1,PPARG,SIRPA
REGULATION OF MONOATOMIC ION TRANSPORT%GOBP%GO:0043269	regulation of monoatomic ion transport	0.0215131799704323	0.0215131799704323	1	CAV1,BIN1,F2R,FXYD5,WNK4,TESC,FHL1,STC1,SLC8A1,MYLK,KCNAB2,STAC2,KCNH2,KCNG1,HOMER3,UBASH3B,CBARP,SNTA1,SCN1B,KCNIP3,JPH2,PML,SCN5A,KCNS3,SPHK2,WNK2,PRKCE,CRACR2A,ADAM23,P2RX5,PER1,NKAIN1,JPH3,TMEM38A
NEGATIVE REGULATION OF TRANSPORT%GOBP%GO:0051051	negative regulation of transport	0.0215131799704323	0.0215131799704323	1	CAV1,BIN1,F2R,WNK4,LIF,GNAI1,ANKRD13A,KLF7,PKDCC,PID1,IL11,SHH,ANXA2,IRS2,STC1,HLA-F,KCNH2,ITGB3,ANXA1,SNX33,RAB11FIP5,CBARP,RHBDF2,PPM1F,ANKRD13B,PRKD1,NECAB2,PRTN3,PRKCE,ADAM23,SIRPA,WDR54,ABCA2,PEA15
PLEURAL MESOTHELIOMA%WIKIPATHWAYS_20260910%WP5087%HOMO SAPIENS	Pleural mesothelioma	0.0217933699114474	0.0217933699114474	1	FOSL1,CSF3,CTGF,LAMB3,EPHA2,CD44,ITGB4,RASSF4,EGFR,FGF2,LAMB1,FZD8,IGF1R,MYC,AJUBA,ROR1,TNNT1,CSF1,LAMA4,ITGB3,LAMC2,LAMA5,ACTG1,PRKAG2,MINK1,FLT1,WNT10B,TGFB1,CDH2,CDH15,WNT10A,TEAD4,NF2,ITGA6,CDKN2A,FZD2,DVL1,NGFR,MAP2K5
PROTEIN LOCALIZATION TO MEMBRANE%GOBP%GO:0072657	protein localization to membrane	0.0217933699114474	0.0217933699114474	1	CAV1,EHD2,NKD2,TESC,RAMP1,RAB6B,EPHA2,LRP4,GRIP2,ZDHHC8,GAS6,TTC7A,SPTBN1,AGRN,SHANK3,KCNIP3,PRKCZ,NMT2,S100A10,CCDC88A,TSPAN33,DVL1,ANK1,NLGN2,ITGB2,OPTN,MACF1,MYADM,PACS1,HGS
NEGATIVE REGULATION OF RECEPTOR SIGNALING PATHWAY VIA STAT%GOBP%GO:1904893	negative regulation of receptor signaling pathway via STAT	0.0222040232972686	0.0222040232972686	1	CAV1,SH2B3,SOCS2,NF2,SOCS3,PPARG,HGS
DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM%REACTOME DATABASE ID RELEASE 97%3560782	Diseases associated with glycosaminoglycan metabolism	0.0222040232972686	0.0222040232972686	1	BGN,CHST3,EXT1,SDC2,GPC1,CHSY1,AGRN,HSPG2,CSPG5
CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS%GOBP%GO:0071363	cellular response to growth factor stimulus	0.0223578550134926	0.0223578550134926	1	ADAMTS7,CD44,EGFR,FGF2,ID1,SPHK1,ZYX,SMAD3,WNT5A,GAS1,PSG9,PDE2A,ANXA1,TGFBR2,SMAD4,BMP7,FLT1,TGFB1,LTBP3,WNT10A,FAM83G,CIB1,PRKD1,MAPT,DDIT4,PGF,RGMB,PPARG,ZFP36L2,MYO1C,HTRA2,MAP2K5,FURIN,SNAI2
NEGATIVE REGULATION OF ENDOCYTOSIS%GOBP%GO:0045806	negative regulation of endocytosis	0.022941963082866	0.022941963082866	1	CAV1,ANKRD13A,ANXA2,SNX33,ANKRD13B,PRKD1,NECAB2,PRTN3,SIRPA,WDR54,ABCA2
NEGATIVE REGULATION OF PROTEIN METABOLIC PROCESS%GOBP%GO:0051248	negative regulation of protein metabolic process	0.0235925220863787	0.0235925220863787	1	CAV1,SERPINE1,TIMP2,IGF2BP2,ADGRB1,BIN1,FBLN1,ERRFI1,NMNAT2,SERPINE2,EGFR,ANXA2,PRR5L,TIMP1,NXN,BACE2,ITM2C,CPEB1,AJUBA,GAS1,P3H1,CRTAP,ITGB3,CSTB,CORO1C,WTIP,PLAU,ISG15,SLIT2,CIB1,RTN4,DUSP7,PLAT,PML,CDKN2A,RGS14,FBXO32,TIMP4,ADARB1,NOP53,DAPK3,MAD2L2,CTSA,DDRGK1,JAK3,FURIN,GADD45A
POSITIVE REGULATION OF PHOSPHATIDYLINOSITOL 3-KINASE/PROTEIN KINASE B SIGNAL TRANSDUCTION%GOBP%GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	0.0242618959720804	0.0242618959720804	1	AXL,F2R,CSF3,EGFR,FGF2,F2RL1,EPHA8,PRR5L,IGF1R,WNT5A,GAS6,FLT1,TGFB1,RTN4,HIP1,TSPYL5,CCDC88A,PRKD1,ERFE,RASD2,CPNE1,MYDGF
LEUKOCYTE DIFFERENTIATION%GOBP%GO:0002521	leukocyte differentiation	0.0246332109458753	0.0246332109458753	1	AXL,CSF3,LIF,EPHA2,TCF7,F2RL1,IL11,SHH,ANXA2,CSF1,ANXA1,TGFBR2,GAS6,TGFB1,CBFA2T3,MYH9,RELB,KLF6,SOCS3,IGSF23,NFIL3,CLCF1,DOCK10,PRTN3,PSMA7,P2RX5,JAG2,DLL1,PPARG,ZFP36L2,JAK3,THOC5
REGULATION OF PHOSPHATIDYLINOSITOL 3-KINASE/PROTEIN KINASE B SIGNAL TRANSDUCTION%GOBP%GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	0.0254491848577632	0.0254491848577632	1	AXL,F2R,CSF3,EGFR,FGF2,F2RL1,EPHA8,PRR5L,TWIST1,IGF1R,SH2B3,WNT5A,GAS6,FLT1,TGFB1,CIB1,RTN4,HIP1,TSPYL5,CCDC88A,PRKD1,ERFE,RASD2,NOP53,CPNE1,MYDGF,PLK3
NEGATIVE REGULATION OF G PROTEIN-COUPLED RECEPTOR SIGNALING PATHWAY%GOBP%GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	0.0260897350145642	0.0260897350145642	1	SERPINE1,ADA,ADM,SH2B3,PDE2A,GRK3,PALM,SLIT3,SLIT2,RGS19,RGS14,APLP1
DEFECTIVE B4GALT7 CAUSES EDS, PROGEROID TYPE%REACTOME DATABASE ID RELEASE 97%3560783	Defective B4GALT7 causes EDS, progeroid type	0.0260897350145642	0.0260897350145642	1	BGN,SDC2,GPC1,AGRN,HSPG2,CSPG5
DEFECTIVE B3GAT3 CAUSES JDSSDHD%REACTOME DATABASE ID RELEASE 97%3560801	Defective B3GAT3 causes JDSSDHD	0.0260897350145642	0.0260897350145642	1	BGN,SDC2,GPC1,AGRN,HSPG2,CSPG5
DEFECTIVE B3GALT6 CAUSES EDSP2 AND SEMDJL1%REACTOME DATABASE ID RELEASE 97%4420332	Defective B3GALT6 causes EDSP2 and SEMDJL1	0.0260897350145642	0.0260897350145642	1	BGN,SDC2,GPC1,AGRN,HSPG2,CSPG5
POSITIVE REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY%GOBP%GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	0.0265494703277098	0.0265494703277098	1	ITGA5,CCBE1,ITGB3,ADGRG1,JCAD
INTEGRIN FAMILY CELL SURFACE INTERACTIONS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%INTEGRIN FAMILY CELL SURFACE INTERACTIONS	Integrin family cell surface interactions	0.0271568271288133	0.0271568271288133	1	ITGA5,ITGB4,ITGA3,ITGAX,ITGB3,ITGA6,ITGB2
CYCLIC NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0009187	cyclic nucleotide metabolic process	0.0271568271288133	0.0271568271288133	1	PDE9A,ADCY1,EPHA2,ADCY7,PDE2A,NPR1,ADCY3
CYCLIC PURINE NUCLEOTIDE METABOLIC PROCESS%GOBP%GO:0052652	cyclic purine nucleotide metabolic process	0.0271568271288133	0.0271568271288133	1	PDE9A,ADCY1,EPHA2,ADCY7,PDE2A,NPR1,ADCY3
POSITIVE REGULATION OF PROTEIN LOCALIZATION%GOBP%GO:1903829	positive regulation of protein localization	0.0278584142516109	0.0278584142516109	1	NKD2,GNAI1,EPHA2,LRP1,EGFR,DOC2B,F2RL1,PRR5L,IRS2,LAMB1,SMAD3,ITGA3,STAC2,WNT5A,ZDHHC8,SNX33,GAS6,TGFB1,CDH2,SPTBN1,ACSL4,NF2,CIB1,RTN4,AMOTL2,CCDC88A,NECAB2,MAPT,PRKCE,DVL1,NLGN2,NGFR,CARD10,CAMK1,USP36,PPARG,DDRGK1,PLK3,HTRA2
REGULATION OF ANATOMICAL STRUCTURE SIZE%GOBP%GO:0090066	regulation of anatomical structure size	0.0281304170117051	0.0281304170117051	1	CAV1,BIN1,F2R,L1CAM,CSF3,SEMA7A,CDC42EP3,ADM,F2RL1,DNM1,KCNMA1,SLC8A1,MYLK,ADORA2B,COTL1,NTN1,CARMIL2,CDH2,SHANK3,CDC42EP1,SLIT2,SSH1,RTN4,TBXA2R,LIMK1,MAPT,SCARB1,PRKCE,ECE1,NPR1,FLII,BRK1,MACF1,MYADM
NEGATIVE REGULATION OF ERK1 AND ERK2 CASCADE%GOBP%GO:0070373	negative regulation of ERK1 and ERK2 cascade	0.0282592547934662	0.0282592547934662	1	FBLN1,SMAD4,DUSP9,SPRY4,SPRED3,TNIP1,DUSP7,RGS14,WNK2,SIRPA
SKIN MORPHOGENESIS%GOBP%GO:0043589	skin morphogenesis	0.0283131614383524	0.0283131614383524	1	ERRFI1,ITGB4,ITGA6,AHDC1
REGULATION OF CHAPERONE-MEDIATED AUTOPHAGY%GOBP%GO:1904714	regulation of chaperone-mediated autophagy	0.0283131614383524	0.0283131614383524	1	EEF1A2,GFAP,CTSA,PLK3
DENDRITE DEVELOPMENT%GOBP%GO:0016358	dendrite development	0.0289928946985868	0.0289928946985868	1	KLF7,LRP4,MAPK8IP2,SDC2,MINK1,BMP7,SHANK3,MAP1B,DOCK10,DVL1,IQSEC1
NEGATIVE REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION%GOBP%GO:0043537	negative regulation of blood vessel endothelial cell migration	0.0297865124802684	0.0297865124802684	1	FGF2,TGFB1,VASH1,TBXA2R,CARD10,PPARG,MAP2K5,GADD45A
NRP1 TRIGGERED SIGNALING IN PANCREATIC CANCER %WIKIPATHWAYS_20260910%WP5144%HOMO SAPIENS	NRP1 triggered signaling in pancreatic cancer	0.0297865124802684	0.0297865124802684	1	CTGF,EGFR,PLXNA2,NFKB2,TGFBR2,SMAD4,FLT1,RELB,SNAI2
FOSPHENYTOIN (ANTIARRHYTHMIC) METABOLISM PATHWAY%SMPDB%SMP0000618	Fosphenytoin (Antiarrhythmic) Metabolism Pathway	0.0300021674993224	0.0300021674993224	1	SNTB1,SNTA1,SCN5A
AMP CATABOLIC PROCESS%GOBP%GO:0006196	AMP catabolic process	0.0300021674993224	0.0300021674993224	1	NT5E,XDH,AMPD3
PURINE METABOLISM%PANTHER PATHWAY%P02769	Purine metabolism	0.0300021674993224	0.0300021674993224	1	NT5E,XDH,AMPD3
REGULATION OF CELL JUNCTION ASSEMBLY%GOBP%GO:1901888	regulation of cell junction assembly	0.0302916541883555	0.0302916541883555	1	CAV1,EPHA2,DLC1,PHLDB2,SYNDIG1,SDC2,ACTG1,CORO1C,AGRN,IL1RAPL2,LRFN4,PPM1F,SLIT1,S100A10,DOCK1,ADAM23,NLGN2,DAPK3,MYO1C,MACF1,IQSEC1,SNAI2,MDGA1
REGULATION OF ENDOTHELIAL CELL PROLIFERATION%GOBP%GO:0001936	regulation of endothelial cell proliferation	0.0311253220684392	0.0311253220684392	1	CAV1,F3,CAV2,FGF2,WNT5A,EGFL7,ITGB3,FLT1,VASH1,APLN,PRKD1,EMC10,NGFR,PPARG,MYDGF,JCAD
REGULATION OF CELLULAR RESPONSE TO GROWTH FACTOR STIMULUS%GOBP%GO:0090287	regulation of cellular response to growth factor stimulus	0.0315931078042767	0.0315931078042767	1	ITGA5,CCBE1,FBN1,CRIM1,PMEPA1,FGF2,NOG,FSTL3,ITGA3,NBL1,ITGB3,GPC1,SMAD4,SPRY4,CDKN1C,SPRED3,CREB3L1,APLN,ADGRG1,SLIT2,IL17RD,ERFE,DLL1,PPARG,FAM89B,SMURF2,JCAD,PCSK6,HGS
PHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000380	Phenytoin (Antiarrhythmic) Action Pathway	0.0315931078042767	0.0315931078042767	1	SNTB1,SLC8A1,KCNH2,HCN4,KCNJ4,ATP1A3,SNTA1,SCN5A,PPIB,TPM2,ABCC8,CACNA1H
REGULATION OF SUBSTRATE ADHESION-DEPENDENT CELL SPREADING%GOBP%GO:1900024	regulation of substrate adhesion-dependent cell spreading	0.0315931078042767	0.0315931078042767	1	FBLN1,CORO1C,RAC3,SPRY4,CIB1,S100A10,DOCK1,MELTF,CSPG5,MYADM
REGULATION OF CYTOSKELETON ORGANIZATION%GOBP%GO:0051493	regulation of cytoskeleton organization	0.0315931078042767	0.0315931078042767	1	CORO2B,BIN1,CSF3,CDC42EP3,GNAI1,DLC1,LRP1,IQCJ-SCHIP1,TUBB4A,SYDE1,F2RL1,FSD1,FHOD3,PHLDB2,FSCN1,NGEF,COTL1,TRIP10,CARMIL2,SMAD4,ACTG1,RAC3,SHANK3,ARAP3,CDC42EP1,MAP1B,RHOF,NF2,SLIT2,SSH1,PPM1F,CIB1,S100A10,CCDC88A,LIMK1,MAPT,PRKCE,KATNB1,DAPK3,FLII,BRK1,NAT9,RAB40B,MYADM,GIT1,NES
NEGATIVE REGULATION OF CELL MOTILITY%GOBP%GO:2000146	negative regulation of cell motility	0.0316209349341626	0.0316209349341626	1	SERPINE1,ADGRB1,FBLN1,DLC1,LRP1,RECK,FGF2,DUSP1,SHH,PHLDB2,TIMP1,STC1,NOG,NBL1,IFITM1,KRT16,CORO1C,TGFB1,LRCH1,VASH1,ADGRG1,NF2,SLIT2,TBXA2R,ADARB1,NGFR,CARD10,PPARG,MAP2K5,GADD45A
APOPTOTIC CELL CLEARANCE%GOBP%GO:0043277	apoptotic cell clearance	0.0323738172259834	0.0323738172259834	1	ADGRB1,TGM2,LRP1,ITGB3,ANXA1,GAS6,SCARB1
NEGATIVE REGULATION OF CELL MIGRATION%GOBP%GO:0030336	negative regulation of cell migration	0.0331067344254265	0.0331067344254265	1	SERPINE1,ADGRB1,DLC1,LRP1,RECK,FGF2,DUSP1,SHH,PHLDB2,TIMP1,STC1,NOG,NBL1,IFITM1,KRT16,CORO1C,TGFB1,LRCH1,VASH1,ADGRG1,NF2,SLIT2,TBXA2R,ADARB1,NGFR,CARD10,PPARG,MAP2K5,GADD45A
REGULATION OF AXONOGENESIS%GOBP%GO:0050770	regulation of axonogenesis	0.0331210361392783	0.0331210361392783	1	L1CAM,SEMA7A,EFNB3,BRSK2,LRP4,NTN1,CDH2,SLIT2,RTN4,LIMK1,MAPT,BRSK1,MACF1
DEFECTIVE EXT1 CAUSES EXOSTOSES 1, TRPS2 AND CHDS%REACTOME DATABASE ID RELEASE 97%3656253	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	0.0344109213764399	0.0344109213764399	1	EXT1,SDC2,GPC1,AGRN,HSPG2
INLB-MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL%REACTOME%R-HSA-8875360.5	InlB-mediated entry of Listeria monocytogenes into host cell	0.0344109213764399	0.0344109213764399	1	SH3GL3,MET,SH3KBP1,SH3GL1,HGS
TGF BETA SIGNALING IN THYROID CELLS FOR EPITHELIAL MESENCHYMAL TRANSITION%WIKIPATHWAYS_20260910%WP3859%HOMO SAPIENS	TGF beta signaling in thyroid cells for epithelial mesenchymal transition	0.0344109213764399	0.0344109213764399	1	TNC,ID1,SMAD4,CDH2,SNAI2
CARBOHYDRATE DERIVATIVE CATABOLIC PROCESS%GOBP%GO:1901136	carbohydrate derivative catabolic process	0.0344109213764399	0.0344109213764399	1	PDE9A,FBXO2,FBXO44,ADA,UPP1,CD44,NT5E,FGF2,SUMF2,HKDC1,PDE2A,GPC1,DPYD,TGFB1,LDHA,ENO2,PFKFB3,XDH,AMPD3,OGG1,M6PR
ENDOTHELIAL CELL DEVELOPMENT%GOBP%GO:0001885	endothelial cell development	0.0344109213764399	0.0344109213764399	1	F2RL1,STC1,ROBO4,COL18A1,PDE2A,MET,AMOTL2,MYADM
ANTIGEN PROCESSING AND PRESENTATION OF ENDOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I VIA ER PATHWAY, TAP-INDEPENDENT%GOBP%GO:0002486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	0.0344109213764399	0.0344109213764399	1	HLA-F,HLA-A,RAET1L,RAET1G,ULBP3
DEFECTIVE EXT2 CAUSES EXOSTOSES 2%REACTOME%R-HSA-3656237.5	Defective EXT2 causes exostoses 2	0.0344109213764399	0.0344109213764399	1	EXT1,SDC2,GPC1,AGRN,HSPG2
NEGATIVE REGULATION OF RECEPTOR INTERNALIZATION%GOBP%GO:0002091	negative regulation of receptor internalization	0.0344109213764399	0.0344109213764399	1	ANKRD13A,ANXA2,ANKRD13B,NECAB2,WDR54
REGULATION OF AMYLOID PRECURSOR PROTEIN BIOSYNTHETIC PROCESS%GOBP%GO:0042984	regulation of amyloid precursor protein biosynthetic process	0.0344109213764399	0.0344109213764399	1	RECK,BACE2,ITM2C,NECAB2,ABCA2
NEGATIVE REGULATION OF CELL GROWTH%GOBP%GO:0030308	negative regulation of cell growth	0.0344109213764399	0.0344109213764399	1	FHL1,GNG4,SMAD3,SMAD4,TGFB1,SIPA1,SLIT3,SLIT2,RTN4,PML,DACT3,DCBLD2,CDKN2A,SPHK2,CCDC85B,NPR1,SH3BP4
ANTIGEN PROCESSING AND PRESENTATION OF ENDOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS I VIA ER PATHWAY%GOBP%GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	0.0344109213764399	0.0344109213764399	1	HLA-F,HLA-A,RAET1L,RAET1G,ULBP3
AP-1 TRANSCRIPTION FACTOR NETWORK%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%AP-1 TRANSCRIPTION FACTOR NETWORK	AP-1 transcription factor network	0.0344109213764399	0.0344109213764399	1	FOSL1,TRIP6,NFATC2,DUSP1,TIMP1,MT2A,MYC,HLA-A,TGFB1,PLAU,CDKN2A,FOSL2
KIDNEY EPITHELIUM DEVELOPMENT%GOBP%GO:0072073	kidney epithelium development	0.0347896998888209	0.0347896998888209	1	WNK4,SOX8,PODXL,FGF2,SIX2,SHH,MYC,BMP7,SLIT2,MYO1E,BASP1
REGULATION OF SMAD PROTEIN SIGNAL TRANSDUCTION%GOBP%GO:0060390	regulation of SMAD protein signal transduction	0.0347896998888209	0.0347896998888209	1	PMEPA1,LRP1,NOG,SMAD3,PSG9,TGFBR2,SMAD4,BMP7,TGFB1,PPARG,FAM89B
ENDODERM DEVELOPMENT%GOBP%GO:0007492	endoderm development	0.0347896998888209	0.0347896998888209	1	COL6A1,ITGA5,LAMB3,HMGA2,COL12A1,DUSP1,LAMB1,DUSP5,ITGB2,MMP15
REGULATION OF LIPID TRANSPORT%GOBP%GO:0032368	regulation of lipid transport	0.0349795632109681	0.0349795632109681	1	CAV1,ANGPTL4,LRP1,C1QTNF1,SHH,ANXA2,IRS2,GPIHBP1,ZDHHC8,ITGB3,GAL,TSPO,PLTP,NMB,PPARG,ABCA2
PROTEOLYSIS%GOBP%GO:0006508	proteolysis	0.0351088851063487	0.0351088851063487	1	F3,CPA4,ADAMTS7,FBXO2,ADAM12,THBD,HTRA1,SHH,TRABD2B,BACE2,ADAM11,ADAMTS16,PLAUR,MMP24,ADAMTS14,CPQ,MMP19,TGFB1,MYH9,ADAM19,PLAU,ADAMTS17,VASH1,BMP1,SEC11A,PCSK1N,PLAT,PRTN3,DPP9,ADAM23,PRRG1,ECE1,AZU1,CPNE1,CTSA,PRSS12,HTRA2,STOML2,MMP15,FURIN,ADAMTS15,PCSK6
REGULATION OF PROTEIN LOCALIZATION TO PLASMA MEMBRANE%GOBP%GO:1903076	regulation of protein localization to plasma membrane	0.0356274069308966	0.0356274069308966	1	WNK4,NKD2,EPHA2,LRP1,EGFR,PKDCC,PID1,ITGA3,STAC2,ZDHHC8,TGFB1,SPTBN1,CIB1,LRRC15,PRKCE
VASCULAR PROCESS IN CIRCULATORY SYSTEM%GOBP%GO:0003018	vascular process in circulatory system	0.0358646638746045	0.0358646638746045	1	CAV1,F2R,LRP1,ADM,F2RL1,KCNMA1,SLC29A4,SLC8A1,MYLK,FABP5,ADORA2B,SLC6A6,PDE2A,TGFB1,SLIT2,TBXA2R,SCARB1,ECE1,SLC4A3,NPR1,AZU1,ABCA2,SLC2A1,SLCO3A1
REGULATION OF BODY FLUID LEVELS%GOBP%GO:0050878	regulation of body fluid levels	0.0367285340828798	0.0367285340828798	1	CAV1,AXL,SERPINE1,F3,F2R,FBLN1,SERPINE2,ADCY1,ADCY7,THBD,ADM,C1QTNF1,F2RL1,RASA3,SH2B3,PLAUR,SAA1,ITGB3,ACTG1,UBASH3B,PLAU,APLN,DGKD,PLAT,PABPC4,NPR1,ADCY3,PRKAR1B
POSITIVE REGULATION OF PROTEIN LOCALIZATION TO MEMBRANE%GOBP%GO:1905477	positive regulation of protein localization to membrane	0.0374009614166424	0.0374009614166424	1	NKD2,EPHA2,LRP1,EGFR,LAMB1,ITGA3,STAC2,ZDHHC8,SPTBN1,CIB1,NECAB2,PRKCE
INTERLEUKIN-4 AND INTERLEUKIN-13 SIGNALING%REACTOME DATABASE ID RELEASE 97%6785807	Interleukin-4 and Interleukin-13 signaling	0.0376983654848689	0.0376983654848689	1	LIF,FGF2,TIMP1,TWIST1,FSCN1,ITGAX,SAA1,MYC,ANXA1,LAMA5,TGFB1,SOCS3,IL4R,ITGB2,JAK3,ZEB1
EBOLA VIRUS INFECTION IN HOST%WIKIPATHWAYS_20260910%WP4217%HOMO SAPIENS	Ebola virus infection in host	0.0376983654848689	0.0376983654848689	1	AXL,CAV2,EGFR,MFGE8,HLA-F,IGF1R,NFKB2,ITGB3,FLNB,ACTG1,HLA-A,RELB,CLTCL1,SOCS3,ITGA6,ACTN1
EGFR1%NETPATH%EGFR1	EGFR1	0.0382431968851103	0.0382431968851103	1	AXL,RIN1,TRIP6,CRIM1,CAV2,EPHA2,ITGB4,EGFR,CAVIN1,ARHGEF4,PHLDB2,MAP3K14,MYC,EEF1A2,ANXA1,FLNB,SH3GL3,CSTB,MINK1,SNX33,UBASH3B,PLEC,MYH9,CDH2,SPRY4,SHB,SOCS3,S100A10,CEBPB,ACTN1,DOCK1,PRKD1,PPP1R14B,SIRPA,DYRK3,PLEKHN1
POSITIVE REGULATION OF BLOOD COAGULATION%GOBP%GO:0030194	positive regulation of blood coagulation	0.0384025741381928	0.0384025741381928	1	SERPINE1,F3,F2R,THBD,PLAU,PLAT
ALPHA6BETA4INTEGRIN%IOB%ALPHA6BETA4INTEGRIN	Alpha6Beta4Integrin	0.0384025741381928	0.0384025741381928	1	LAMB3,ITGB4,EGFR,LAMB1,NTN1,LAMC2,LAMA5,PLEC,CD151,ITGA6
REGULATION OF FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PATHWAY%GOBP%GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	0.0384025741381928	0.0384025741381928	1	FGF2,NOG,GPC1,SPRY4,CREB3L1,APLN
POSITIVE REGULATION OF HEMOSTASIS%GOBP%GO:1900048	positive regulation of hemostasis	0.0384025741381928	0.0384025741381928	1	SERPINE1,F3,F2R,THBD,PLAU,PLAT
EXTRACELLULAR MATRIX ASSEMBLY%GOBP%GO:0085029	extracellular matrix assembly	0.0384025741381928	0.0384025741381928	1	PXDN,GAS6,QSOX1,TNXB,TGFB1,MFAP4
NEGATIVE REGULATION OF LOCOMOTION%GOBP%GO:0040013	negative regulation of locomotion	0.0384025741381928	0.0384025741381928	1	SERPINE1,ADGRB1,FBLN1,DLC1,LRP1,RECK,FGF2,DUSP1,SHH,PHLDB2,TIMP1,STC1,NOG,NBL1,IFITM1,KRT16,CORO1C,TGFB1,LRCH1,VASH1,ADGRG1,NF2,SLIT2,TBXA2R,ADARB1,NGFR,CARD10,PPARG,MAP2K5,GADD45A
REGULATION OF CYTOKINE PRODUCTION INVOLVED IN IMMUNE RESPONSE%GOBP%GO:0002718	regulation of cytokine production involved in immune response	0.0384025741381928	0.0384025741381928	1	SEMA7A,F2RL1,HLA-F,WNT5A,SECTM1,HLA-A,TGFB1,PRKCZ,RAET1G,SPHK2,TICAM1,NR4A3,JAK3
PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS FSGS %WIKIPATHWAYS_20260910%WP2572%HOMO SAPIENS	Primary focal segmental glomerulosclerosis FSGS	0.0384025741381928	0.0384025741381928	1	ITGB4,PLAUR,ITGB3,LAMA5,TGFB1,MYH9,CDH2,AGRN,CDKN1C,CD151,MYO1E
REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO%REACTOME DATABASE ID RELEASE 97%428542	Regulation of commissural axon pathfinding by SLIT and ROBO	0.0409385618429267	0.0409385618429267	1	NTN1,SLIT3,SLIT2,SLIT1
MUSCLE STRUCTURE DEVELOPMENT%GOBP%GO:0061061	muscle structure development	0.0416351703435534	0.0416351703435534	1	CAV1,COL6A1,BIN1,FHL1,ADAM12,CAV2,PDLIM7,POPDC3,FHOD3,NOG,SLC8A1,MYLK,EPAS1,MAPK12,COL6A3,TNNT1,SMAD4,TGFB1,FHL3,TEAD4,MYPN,SPEG,ACTN1,DOCK1,IGSF8,BASP1,DLL1,FLII,MYL6B,ADAMTS15,PDLIM2,CACNA1H
REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY%GOBP%GO:1904375	regulation of protein localization to cell periphery	0.0416781475261384	0.0416781475261384	1	WNK4,NKD2,GNAI1,EPHA2,LRP1,EGFR,PKDCC,PID1,ITGA3,STAC2,ZDHHC8,TGFB1,SPTBN1,CIB1,LRRC15,PRKCE,ABCA2
CELLULAR RESPONSE TO OXYGEN LEVELS%GOBP%GO:0071453	cellular response to oxygen levels	0.0418987133665078	0.0418987133665078	1	CAV1,NDRG1,BNIP3,TWIST1,EPAS1,CPEB1,MYC,BMP7,TGFB1,ATG7,NOP53,PPARG,EGLN3,LMNA
REGULATION OF RECEPTOR-MEDIATED ENDOCYTOSIS%GOBP%GO:0048259	regulation of receptor-mediated endocytosis	0.0418987133665078	0.0418987133665078	1	SERPINE1,C3,ANKRD13A,RSPO1,ANXA2,ITGB3,APLN,DGKD,ANKRD13B,HIP1,NECAB2,WDR54,ABCA2,IQSEC1
A6B1 AND A6B4 INTEGRIN SIGNALING%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%A6B1 AND A6B4 INTEGRIN SIGNALING	a6b1 and a6b4 Integrin signaling	0.0420991405340302	0.0420991405340302	1	LAMB3,ITGB4,EGFR,LAMB1,LAMA4,LAMC2,LAMA5,MET,ITGA6
REGULATION OF ERBB SIGNALING PATHWAY%GOBP%GO:1901184	regulation of ERBB signaling pathway	0.0433830888449701	0.0433830888449701	1	ERRFI1,EGFR,PLAUR,TGFB1,RHBDF2,SPRY4,PLAU,DGKD,RTN4,HIP1,CCDC88A,WDR54
POSITIVE REGULATION OF SUPEROXIDE ANION GENERATION%GOBP%GO:0032930	positive regulation of superoxide anion generation	0.0433830888449701	0.0433830888449701	1	F2RL1,TGFB1,MAPT,PRKCE,ITGB2
MYELOID CELL DIFFERENTIATION%GOBP%GO:0030099	myeloid cell differentiation	0.0433830888449701	0.0433830888449701	1	MXRA7,CSF3,LIF,EPHA2,F2RL1,IL11,ANXA2,SH2B3,EPAS1,CSF1,TGFBR2,CBFA2T3,MYH9,FTL,SELENOW,IGSF23,CIB1,CEBPB,ACTN1,PRTN3,P2RX5,PPARG,THOC5,DYRK3
MESODERM FORMATION%GOBP%GO:0001707	mesoderm formation	0.0433830888449701	0.0433830888449701	1	HMGA2,ITGB4,SIX2,ITGA3,ITGB3,AHDC1,EYA2
HALLMARK_MYOGENESIS%MSIGDBHALLMARK%HALLMARK_MYOGENESIS%MSIGDBHALLMARK%HALLMARK_MYOGENESIS%MSIGDBHALLMARK%HALLMARK_MYOGENESIS	HALLMARK_MYOGENESIS%MSigdbHallmark%HALLMARK_MYOGENESIS	0.0433830888449701	0.0433830888449701	1	BIN1,FHL1,ADAM12,ITGB4,FGF2,PDLIM7,SPHK1,MYLK,KIFC3,MAPK12,TNNT1,TGFB1,MYH9,AGRN,TEAD4,SPEG,PTP4A3,FLII,MYO1C,MYL6B,CACNA1H
HALLMARK_HEDGEHOG_SIGNALING%MSIGDBHALLMARK%HALLMARK_HEDGEHOG_SIGNALING%MSIGDBHALLMARK%HALLMARK_HEDGEHOG_SIGNALING%MSIGDBHALLMARK%HALLMARK_HEDGEHOG_SIGNALING	HALLMARK_HEDGEHOG_SIGNALING%MSigdbHallmark%HALLMARK_HEDGEHOG_SIGNALING	0.0433830888449701	0.0433830888449701	1	L1CAM,SHH,ETS2,CNTFR,MYH9,PML,SLIT1
REGULATION OF NEURON PROJECTION ARBORIZATION%GOBP%GO:0150011	regulation of neuron projection arborization	0.0433830888449701	0.0433830888449701	1	NTNG1,WNT5A,NTNG2,DVL1,MACF1
MIR TARGETED GENES IN LYMPHOCYTES%WIKIPATHWAYS_20260910%WP2004%HOMO SAPIENS	miR targeted genes in lymphocytes	0.0433830888449701	0.0433830888449701	1	AXL,MRC2,SERPINE2,EGFR,NT5E,FGF2,PDLIM7,ANXA2,PXDN,NXN,LY6K,SH3BGRL3,TNFAIP2,MAPK12,TGFBR2,LAMC2,CORO1C,TMED3,P4HA2,CDKN1C,GYS1,UNC93B1,NF2,RTN4,CYR61,CDKN2A,CEBPB,PHC2,PPIB,ATP6V1F,MYO1E,FMNL2,TMEM43,HMGA1,TRMT1,SH3BP4
DENDRITE MORPHOGENESIS%GOBP%GO:0048813	dendrite morphogenesis	0.0433830888449701	0.0433830888449701	1	KLF7,LRP4,MAPK8IP2,SDC2,MINK1,SHANK3,DOCK10,DVL1
NEGATIVE REGULATION OF CELL DIFFERENTIATION%GOBP%GO:0045596	negative regulation of cell differentiation	0.0433830888449701	0.0433830888449701	1	CAV1,DPYSL5,COL5A1,ADAMTS7,FBN1,EFNB3,CRIM1,SOX8,NFATC2,EGFR,ABCA1,SHH,NOG,LGALS1,TWIST1,SMAD3,FSTL3,STAC2,WNT5A,MYC,LRP4,CNTFR,ITGB3,ANXA1,SMAD4,BMP7,WNT10B,TGFB1,SPRED3,CIB1,RTN4,IL17RD,ERFE,PSMA7,CCDC85B,RFLNB,MAD2L2,DLL1,PPARG,ZFP36L2,JAK3,ZEB1,PRICKLE1,SNAI2
REGULATION OF SUPEROXIDE ANION GENERATION%GOBP%GO:0032928	regulation of superoxide anion generation	0.0433830888449701	0.0433830888449701	1	F2RL1,TGFB1,MAPT,PRKCE,ITGB2
BETA2 INTEGRIN CELL SURFACE INTERACTIONS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%BETA2 INTEGRIN CELL SURFACE INTERACTIONS	Beta2 integrin cell surface interactions	0.0433830888449701	0.0433830888449701	1	TGFBI,C3,PLAUR,ITGAX,PLAU,PLAT,ITGB2
ANTIGEN PROCESSING AND PRESENTATION OF ENDOGENOUS PEPTIDE ANTIGEN VIA MHC CLASS IB%GOBP%GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	0.0433830888449701	0.0433830888449701	1	HLA-F,HLA-A,RAET1L,RAET1G,ULBP3
INTERACTION BETWEEN L1 AND ANKYRINS%REACTOME%R-HSA-445095.2	Interaction between L1 and Ankyrins	0.0433830888449701	0.0433830888449701	1	L1CAM,NFASC,SCN1B,SPTBN1,SCN5A,SCN8A,ANK1
GLIOGENESIS%GOBP%GO:0042063	gliogenesis	0.0433830888449701	0.0433830888449701	1	SOX8,LRP1,SHH,LAMB1,MMP24,GPC1,CDH2,ADGRG1,NF2,RTN4,MAPT,CNP,CSPG5,AZU1,DLL1,ABCA2
5Q35 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5380%HOMO SAPIENS	5q35 copy number variation	0.0440980260937401	0.0440980260937401	1	GNAI1,UNC5A,PDLIM7,IGF1R,MYC,DBN1,NTN1,DDX41,HIC2,RGS14,PRR7,GPRIN1,NOP16,COX5A
PLASMA MEMBRANE ORGANIZATION%GOBP%GO:0007009	plasma membrane organization	0.0440980260937401	0.0440980260937401	1	CAV1,COL5A1,BIN1,EHD2,CAV2,TRIP10,SNX33,DMKN,MYH9,SPTBN1,ANO7,RAB3A,CNP,STX2
MIR TARGETED GENES IN MUSCLE CELL%WIKIPATHWAYS_20260910%WP2005%HOMO SAPIENS	miR targeted genes in muscle cell	0.0442973836537381	0.0442973836537381	1	AXL,MRC2,ITGB4,EGFR,NT5E,FGF2,PDLIM7,PHLDB2,PXDN,NXN,SH3BGRL3,TNFAIP2,MAPK12,CSF1,TGFBR2,LAMC2,CORO1C,TMED3,P4HA2,NF2,RTN4,CYR61,CEBPB,PPIB,CAMTA1,MYO1E,FMNL2,TMEM43,HMGA1,SH3BP4
LPA RECEPTOR MEDIATED EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%LPA RECEPTOR MEDIATED EVENTS	LPA receptor mediated events	0.0457945621237419	0.0457945621237419	1	TRIP6,ADCY1,GNAI1,ADCY7,EGFR,ADRA1B,PRKD1,MAPT,PRKCE,ADCY3,PLCB3
REGULATION OF SUPEROXIDE METABOLIC PROCESS%GOBP%GO:0090322	regulation of superoxide metabolic process	0.0459770905619954	0.0459770905619954	1	F2RL1,BMP7,TGFB1,MAPT,PRKCE,ITGB2
POSITIVE REGULATION OF PROTEIN PROCESSING%GOBP%GO:0010954	positive regulation of protein processing	0.0459770905619954	0.0459770905619954	1	CCBE1,NKD2,ANXA2,MYH9,S100A10,MELTF
NEGATIVE REGULATION OF RECEPTOR SIGNALING PATHWAY VIA JAK-STAT%GOBP%GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	0.0459770905619954	0.0459770905619954	1	CAV1,SH2B3,SOCS2,NF2,SOCS3,HGS
REGULATION OF PROTEIN LOCALIZATION TO MEMBRANE%GOBP%GO:1905475	regulation of protein localization to membrane	0.0467273209193105	0.0467273209193105	1	WNK4,NKD2,EPHA2,LRP1,EGFR,PKDCC,PID1,LAMB1,ITGA3,STAC2,ZDHHC8,GPC1,TGFB1,SPTBN1,CIB1,NECAB2,LRRC15,PRKCE
CELL-CELL COMMUNICATION%REACTOME DATABASE ID RELEASE 97%1500931	Cell-Cell communication	0.0467337253048222	0.0467337253048222	1	ANGPTL4,LAMB3,ITGB4,ARHGEF4,FBLIM1,TWIST1,PARVB,FOXQ1,MYC,POMT1,CLDN23,LAMC2,PVR,SIRPB1,PLEC,CDH2,SPTBN1,ADAM19,CDH15,SDK2,CD151,SEC11A,RSU1,ITGA6,ACTN1,DOCK1,PSMA7,SIRPA,CADM1,ZEB1,FURIN,SNAI2,PCSK6
INTEGRATIVE ANALYSIS OF TREG GLIAL INTERACTIONS %WIKIPATHWAYS_20260910%WP5561%HOMO SAPIENS	Integrative Analysis of Treg Glial Interactions	0.0478058061276	0.0478058061276	1	MCAM,CD44,EGFR,HTR7,IGF1R,NFKB2,FAM20C,ITGB3,TGFBR2,TGFB1,SOCS3,CNP,JAK3,SIRPA
REGULATION OF BLOOD VESSEL ENDOTHELIAL CELL MIGRATION%GOBP%GO:0043535	regulation of blood vessel endothelial cell migration	0.0481663589517772	0.0481663589517772	1	EPHA2,FGF2,ANXA1,TGFB1,VASH1,CIB1,TBXA2R,PRKD1,CARD10,PPARG,MAP2K5,JCAD,GADD45A
REGULATION OF LEUKOCYTE DIFFERENTIATION%GOBP%GO:1902105	regulation of leukocyte differentiation	0.0486410674660456	0.0486410674660456	1	AXL,FBN1,TESC,LIF,TCF7,SHH,SMARCD3,LGALS1,FSTL3,STAC2,MYC,PSG9,CSF1,ANXA1,TGFBR2,GAS6,CORO1C,UBASH3B,PRDM1,TGFB1,TM4SF19,PRKCZ,IL4R,CEBPB,ERFE,PSMA7,ZFP36L2,DDRGK1,JAK3
ENDODERMAL CELL DIFFERENTIATION%GOBP%GO:0035987	endodermal cell differentiation	0.0496751575313111	0.0496751575313111	1	COL6A1,ITGA5,LAMB3,HMGA2,COL12A1,LAMB1,ITGB2,MMP15
SYNDECAN-1-MEDIATED SIGNALING EVENTS%PATHWAY INTERACTION DATABASE NCI-NATURE CURATED DATA%SYNDECAN-1-MEDIATED SIGNALING EVENTS	Syndecan-1-mediated signaling events	0.0496751575313111	0.0496751575313111	1	COL6A1,COL6A2,COL5A1,COL6A3,LAMA5,MET,TGFB1,PPIB
REGULATION OF MIRNA TRANSCRIPTION%GOBP%GO:1902893	regulation of miRNA transcription	0.0499235811796216	0.0499235811796216	1	FOSL1,EGFR,FGF2,TWIST1,SMAD3,MYC,TGFB1,APLN,PPARD,NGFR,PPARG
MESODERM MORPHOGENESIS%GOBP%GO:0048332	mesoderm morphogenesis	0.0499235811796216	0.0499235811796216	1	HMGA2,ITGB4,SIX2,ITGA3,ITGB3,AHDC1,EYA2
POSITIVE REGULATION OF ERBB SIGNALING PATHWAY%GOBP%GO:1901186	positive regulation of ERBB signaling pathway	0.0499235811796216	0.0499235811796216	1	PLAUR,TGFB1,PLAU,DGKD,RTN4,HIP1,CCDC88A
POSITIVE REGULATION OF PROTEIN LOCALIZATION TO CELL PERIPHERY%GOBP%GO:1904377	positive regulation of protein localization to cell periphery	0.0499235811796216	0.0499235811796216	1	NKD2,GNAI1,EPHA2,LRP1,EGFR,ITGA3,STAC2,ZDHHC8,SPTBN1,CIB1,PRKCE
HALLMARK_P53_PATHWAY%MSIGDBHALLMARK%HALLMARK_P53_PATHWAY%MSIGDBHALLMARK%HALLMARK_P53_PATHWAY%MSIGDBHALLMARK%HALLMARK_P53_PATHWAY	HALLMARK_P53_PATHWAY%MSigdbHallmark%HALLMARK_P53_PATHWAY	0.0499235811796216	0.0499235811796216	1	F2R,PROCR,ADA,LIF,EPHA2,ITGB4,SPHK1,S100A4,PITPNC1,TGFB1,RHBDF2,S100A10,COQ8A,CDKN2A,PPP1R15A,DDIT4,JAG2,PLK3,MAPKAPK3,AEN,GADD45A,EPS8L2