Bioinformatics of Genomic Medicine 2017 Pre-Work

Install these tools before the workshop:

1) A robust text editor.

2) A file decompression tool.

  • For Windows/PC – 7zip.
  • For Linux – gzip.
  • For Mac – already there.

3) A robust internet browser such as Firefox or Safari (Internet Explorer and Chrome are not recommended because of Java issues).

4) SSH client - Mac and Linux users already have a command line ssh program that can be run from the terminal. For Windows users, please download PuTTY.

5) SCP/SFTP client - We will be moving data from the servers to the student laptops for visualization. Mac and Linux users already have a command line scp and sftp program. For Windows users, please install WinSCP.

6) A PDF viewer (Adobe Acrobat or equivalent).

7) Latest version of R and RStudio. If asked to also install git, select yes.

8) Install the BioConductor core packages. To do this, open RStudio and type the following at the > prompt:

source("http://bioconductor.org/biocLite.R");
biocLite();

9) Install some workshop specific packages in RStudio. At the > prompt, type:

install.packages("SNFtool");
install.packages("gplots");
install.packages("RColorBrewer");
install.packages("glmnet");
install.packages("ggplot2");
install.packages("reshape2");
install.packages("pROC");
install.packages("caret");
install.packages("matrixStats");
source("http://bioconductor.org/biocLite.R");
biocLite("minfi");
biocLite("bumphunter");
biocLite("limma");
biocLite("lumi");
biocLite("sva");

Read these papers before the workshop:

The Human Phenotype Ontology: A Tool for Annotating and Analyzing Human Hereditary Disease
PhenoTips: patient phenotyping software for clinical and research use
IHEC Data portal

Do these tutorials before the workshop:

1) R Preparation tutorials: You are expected to have completed the following tutorials in R beforehand. The tutorial should be very accessible even if you have never used R before.

2) UNIX Preparation tutorials:

3) Sequencing Terminology