Bioinformatics for Cancer Genomics 2019

Welcome

Welcome to Bioinformatics for Cancer Genomics 2019.

The course schedule can be found here.

Meet your faculty here

CLASS MATERIALS: You can download the printed course manual here.
Lecture 1 from Trevor
Lecture 3 from Francis


Pre-Workshop Materials

Laptop Setup Instructions

Instructions to setup your laptop can be found here.

Pre-workshop Tutorials

Pre-readings and pre-work can be found here here.
It is in your best interest to complete these before the workshop.


Class Photo

Class Photo


Day 1

Welcome

Michelle Brazas

Module 1: Introduction to Cancer Genomics

Trevor Pugh

Lecture

Module 2: Ethics of Data Usage and Security

Mark Phillips

Lecture

Module 3: Databases and Visualization Tools

Francis Ouellette

Lecture

Module 3 Lab: IGV

Heather Gibling

Lab Practical

Logging into the Cloud

Zhibin Lu

Lecture

Lab Practical: Connecting to the Cloud

  • We have set up instances on the Amazon cloud - one for each student. In order to log in to your instance, you will need a security certificate. If you plan on using Linux or Mac OS X, please download CBWCG.pem from Slack; Otherwise if you plan on using Windows (with Putty), please download CBWCG.ppk from Slack.
    Mac Key
    Windows Key

Unix and R review

Heather Gibling

Assignment


Day 2

Module 4: Genome Alignment

Jared Simpson

Lecture

Lab Practical

Module 5: Genome Assembly

Jared Simpson

Lecture

Lab Practical

Supplemental

Module 6: Copy Number Variants

Sorana Morrissy

Lecture
Lecture in PPT

Updated Lecture

Integrative Assignment

Assignment


Day 3

Module 6 Lab

Sorana Morrissy

Lab Practical

Module 7: Somatic Mutations and Annotations

Sorana Morrissy

Lecture
Lecture in PPT
Updated Lecture

Lab Practical

Module 8: Gene Expression Profiling

Florence Cavalli

Lecture
Lecture in PPT

Integrative Assignment

Assignment


Day 4

Module 8 Lab

Florence Cavalli

Lab Practical

Module 9: Gene Fusion and Rearrangements

Brian Haas

Lecture
Lecture in PPT

Lab Practical - CTAT Fusion Toolkit

Lab Practical - DISCASM and GMAP-Fusion

Module 10: Genes to Pathways

Jüri Reimand

Lecture
Lecture in PPT

Lab Practical - gProfiler

Data Sets - Genelist_GBM.txt
Data Sets - Genelist_KIRC.txt
Data Sets - hsapiens.pathways.NAME.gmt


Day 5

Module 11: Variants to Networks

Robin Haw

Lecture
Lecture in PPT

Lab Lecture

Lab Practical

Module 12: Integration of Clinical Data

Lauren Erdman

Lecture
Lecture in PPT

Lab Practical

Lab Script

Data for lab part 1
Data for lab part 2

Post Workshop

Post workshop content for data sets, docker containers, AWS image, tools and install instructions can be found here


Thank you for attending the Bioinformatics for Cancer Genomics workshop! Help us make this workshop better by filling out our survey.